ID N1RP00_FUSC4 Unreviewed; 794 AA.
AC N1RP00;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 03-MAY-2023, entry version 40.
DE SubName: Full=Alpha-actinin-like protein 1 {ECO:0000313|EMBL:EMT63985.1};
GN ORFNames=FOC4_g10010466 {ECO:0000313|EMBL:EMT63985.1};
OS Fusarium oxysporum f. sp. cubense (strain race 4) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=2502994 {ECO:0000313|EMBL:EMT63985.1, ECO:0000313|Proteomes:UP000016929};
RN [1] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- SIMILARITY: Belongs to the alpha-actinin family.
CC {ECO:0000256|ARBA:ARBA00010255}.
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DR EMBL; KB726992; EMT63985.1; -; Genomic_DNA.
DR AlphaFoldDB; N1RP00; -.
DR STRING; 1229665.N1RP00; -.
DR HOGENOM; CLU_005217_0_1_1; -.
DR Proteomes; UP000016929; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd21215; CH_SpAIN1-like_rpt1; 1.
DR CDD; cd21291; CH_SpAIN1-like_rpt2; 1.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR014837; EF-hand_Ca_insen.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF08726; EFhand_Ca_insen; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM01184; efhand_Ca_insen; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 2.
DR SUPFAM; SSF46966; Spectrin repeat; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000016929};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 247..352
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 361..467
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 157..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 764..794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 794 AA; 89848 MW; ED5BAA85D5E29B35 CRC64;
MDATKDSAQA FQGMLPLQPG NVEGNEKFPN FCLHADAQSS DDCDCNQQHR YQENKEGYYV
YQTDLSINNN SNQHHQHFHN SPSASISASS RLSYISTVSA SASSSSSRIS TASFESLPIT
PISVFEASPH TPRSLSNRLS SPVTGFIARR RAFTQDSCSL SYSPPSSPTP RTRRDKSQLH
AARVQRSGSR TTNTTFLLGL QIGKQSTNSR RFPPSASTPA DALAAVEPPH DQKLTRMAFA
EQQRWVTVQQ KTFTKWLNTK IEARNLEVKD LVKDLSDGVM LIHLLECLSH ESLGRYASKP
KLRVQKFENA NLALDFVKSR GIQMTNIGAE DVVDGNQKIV LGLIWTLILR FTISDINEEG
MSAKEGLLLW CQRKTACYDE VEVRDFSASW NDGLAFCALL DIHRPDLIDY DALDKKDHRG
NMQLAFDIAH KEIGIPKLLD VEDVCDVAKP DERSLMTYIA YWFHAFSQME KVENAGRRVE
KFVNNMQGAW EMQSAYERRM RALLQAIQEQ IEVWKQATFE GTYADAKAQS NQFFEYKKGK
KRQWVAEKSD LATLLGNIKT KLGTYRLRPY DPPAELSLDA LERKWAELAS NEMTRAQLIN
ETIRDIKNAL RKSFADKAND FAMALNTMQL AISGLDGDVE DQLHHELEFS AALASLGLVF
SEDEMHDYFL ETSGGRDYVT FEQFIRFMVD VTEDQNTAEQ VFQSFREVAD GKPYVTEMDL
RHSLVPDEVI DQLIEIMPPH SGPDMSEDRG MPQYDYISFM EKLINDQNNQ QENPEATQQN
RSDAEPQSPH TNGV
//
