ID N1S8M3_FUSC4 Unreviewed; 640 AA.
AC N1S8M3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:EMT74036.1};
GN ORFNames=FOC4_g10001993 {ECO:0000313|EMBL:EMT74036.1};
OS Fusarium oxysporum f. sp. cubense (strain race 4) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=2502994 {ECO:0000313|EMBL:EMT74036.1, ECO:0000313|Proteomes:UP000016929};
RN [1] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 4 {ECO:0000313|Proteomes:UP000016929};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; KB726218; EMT74036.1; -; Genomic_DNA.
DR AlphaFoldDB; N1S8M3; -.
DR STRING; 1229665.N1S8M3; -.
DR HOGENOM; CLU_002865_4_1_1; -.
DR Proteomes; UP000016929; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF100; DEHYDROGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G00630)-RELATED; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000016929};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..640
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004111378"
FT DOMAIN 122..387
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 493..630
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
FT BINDING 294
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 640 AA; 68923 MW; E59B805288891B6C CRC64;
MRHAFFAGLL AAPASVCAVA LTGYEYIVVG SGAGGGPLAA RLALAGHKTL LIEAGDDYAS
LNYTVPAYSA NASEDPEISW NFFVRHYADD ERQARDYKTT YDTPNGEYTG LNPPEGAEIK
GTLYPRTQAL GGCTAHNALI AVYPHQSDFE YIASLTGDDS WSADNMRKYF VKAEDNNYRP
AGEAGHGYDG WLSTETAPLS IPLNDEQLLS ILSGGAVALS EMTGKNITMD GLIADDANAD
TLARDQEPGF YQIPLSTKDA SRIGPRELIL SVRDAKHPNG TKKYPLDVRT NCYVTKVTFD
DSKPPRANGV EFLDGKHLYK ASPLATGAAG TPGNATASRE VVVAGGVYNT PQILKLSGIG
PADELKKFDI PVISDLPGVG TNLQDHYEIS VQGTLENNFT SFDGCTFGLF TDEDPCVNRW
RAPVDGDHGI YSSSGLAASM FYKSSTAEKD NFDIFAFGGP VNFRGYFPQY AVNATIEHNW
FSWAILKAHP RNNAGEVLLQ SADPLDMPAI TFNYFDTGNG DYSADLQALY EAVELTRSAL
ASQAVNVTEV LPGADVTSQK DIETYVKDVA WGHHASSTCP IGADDDKMAV LDSKFRVRGV
AGLRVVDASV YPRIPGTFTA VSTYMVAEKA ADIMLAELEE
//
