ID N1UIB1_LEPIR Unreviewed; 127 AA.
AC N1UIB1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=N-(5'-phosphoribosyl)anthranilate isomerase {ECO:0000256|ARBA:ARBA00022272};
DE EC=5.3.1.24 {ECO:0000256|ARBA:ARBA00012572};
DE Flags: Fragment;
GN ORFNames=LEP1GSC115_3341 {ECO:0000313|EMBL:EMY26013.1};
OS Leptospira interrogans serovar Australis str. 200703203.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1085541 {ECO:0000313|EMBL:EMY26013.1, ECO:0000313|Proteomes:UP000012220};
RN [1] {ECO:0000313|EMBL:EMY26013.1, ECO:0000313|Proteomes:UP000012220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=200703203 {ECO:0000313|EMBL:EMY26013.1,
RC ECO:0000313|Proteomes:UP000012220};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Picardeau M., Werts C., Goarant C.,
RA Vinetz J.M., Sutton G.G., Nierman W.C., Fouts D.E.;
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-
CC carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate;
CC Xref=Rhea:RHEA:21540, ChEBI:CHEBI:18277, ChEBI:CHEBI:58613;
CC EC=5.3.1.24; Evidence={ECO:0000256|ARBA:ARBA00001164};
CC -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC tryptophan from chorismate: step 3/5. {ECO:0000256|ARBA:ARBA00004664}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMY26013.1}.
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DR EMBL; AHNY02000106; EMY26013.1; -; Genomic_DNA.
DR AlphaFoldDB; N1UIB1; -.
DR UniPathway; UPA00035; UER00042.
DR Proteomes; UP000012220; Unassembled WGS sequence.
DR GO; GO:0004640; F:phosphoribosylanthranilate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0000162; P:tryptophan biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00405; PRAI; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR HAMAP; MF_00135; PRAI; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR001240; PRAI_dom.
DR InterPro; IPR011060; RibuloseP-bd_barrel.
DR InterPro; IPR044643; TrpF_fam.
DR PANTHER; PTHR42894; N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE; 1.
DR PANTHER; PTHR42894:SF1; N-(5'-PHOSPHORIBOSYL)ANTHRANILATE ISOMERASE; 1.
DR Pfam; PF00697; PRAI; 1.
DR SUPFAM; SSF51366; Ribulose-phoshate binding barrel; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000313|EMBL:EMY26013.1}.
FT DOMAIN 38..121
FT /note="N-(5'phosphoribosyl) anthranilate isomerase (PRAI)"
FT /evidence="ECO:0000259|Pfam:PF00697"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EMY26013.1"
SQ SEQUENCE 127 AA; 14227 MW; 8CE1595E4303DA65 CRC64;
HDLVQWVWDD PLINRKKLLY KRQICSYRVQ TQIHDQDLKD IAAEFLILDS YSKGVGGGTG
ETFNWELISK VKRKFLLAGG LDPSNVVNAI EIVKPFGVDV ASGVESSPGI KDPQKVIQFI
RNVKSTS
//
