ID   N1USB1_LEPIR            Unreviewed;      2344 AA.
AC   N1USB1;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=RHS repeat-associated core domain protein {ECO:0000313|EMBL:EMY24775.1};
GN   ORFNames=LEP1GSC115_1967 {ECO:0000313|EMBL:EMY24775.1};
OS   Leptospira interrogans serovar Australis str. 200703203.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1085541 {ECO:0000313|EMBL:EMY24775.1, ECO:0000313|Proteomes:UP000012220};
RN   [1] {ECO:0000313|EMBL:EMY24775.1, ECO:0000313|Proteomes:UP000012220}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=200703203 {ECO:0000313|EMBL:EMY24775.1,
RC   ECO:0000313|Proteomes:UP000012220};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Picardeau M., Werts C., Goarant C.,
RA   Vinetz J.M., Sutton G.G., Nierman W.C., Fouts D.E.;
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMY24775.1}.
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DR   EMBL; AHNY02000176; EMY24775.1; -; Genomic_DNA.
DR   BioCyc; LINT1085541:G11IQ-3493-MONOMER; -.
DR   Proteomes; UP000012220; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.180.10.10; RHS repeat-associated core; 3.
DR   InterPro; IPR028994; Integrin_alpha_N.
DR   InterPro; IPR022385; Rhs_assc_core.
DR   InterPro; IPR031325; RHS_repeat.
DR   InterPro; IPR003284; Sal_SpvB.
DR   InterPro; IPR006530; YD.
DR   NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR   NCBIfam; TIGR01643; YD_repeat_2x; 1.
DR   PANTHER; PTHR32305; -; 1.
DR   PANTHER; PTHR32305:SF15; PROTEIN RHSA-RELATED; 1.
DR   Pfam; PF05593; RHS_repeat; 1.
DR   Pfam; PF03534; SpvB; 1.
DR   SUPFAM; SSF69318; Integrin alpha N-terminal domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT   TRANSMEM        1923..1941
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   2344 AA;  256647 MW;  33F41F97BC035013 CRC64;
     MNKRTGKSLY ETLCRIFFLS ISLLFLFNFS LLSGIQNVFS SVASAIAGGI PQKLPTLQAG
     LDGSANTQIE IELPPGKVVP SLSLSYNSNV GNTIVGMGWS LNGLPTVSRN PSLGINYNGS
     DSYVSSLAGE LIDVSGNKTI YHSKKESYIK FEPQGTCGDG PCTWMATEKD GRRFIFGGSI
     DSRIPALGRT AGSIREWALS REEDSHGNGY DVNYTPVDVN SGDYYPNTIT YNDRTIRFNF
     ENRNDKIPNY SLGTMERIQK RLDTIEIRVG GNVLRTYDLD YSYGPVTGRS IFRKLKQDGN
     NTFGSENFAD LDFNYTNHSG SFSPGHLDYQ NLSSVSNMNV FIPNIAVDAM NFILNGNLPY
     HPSALDSNID ASLQYVVKVP VPDRNACNIG FASCLCAAIP VCWGGNQHFL EYLAGNCWSF
     LGWGGLGSCE VGVDSALTAW LPMDLNGDGI VDFATLNGNE ANGSIHLVGH IQKIGQSAIT
     FNGPNIPIHY NTFYQVVDLN GDGKTDFVYE DNGRLWGIYS TGGNFTSPVL FGNVNLNSAN
     RDMHVFSPYE YKFHYGPNNT TPLASDRASK DFFGDVNGDG LSDFIHNNGG SFSIYINRET
     YFDNPIGIGG GGDFYLNSMI DFTGDGKADY VQLVVTYDNS TLTALQSQKT ALDTLMAQYQ
     TEHTRVKAVV DQMPTPTTHA NIDDTEFENL LAYLTANGYD SLSDSLESDG KDYPYTPSTV
     TGLQSILENI VSARLNFVGQ QSYALNNQIA AIYAQGNLGQ ATYALQIRTF NLSNGTSQNV
     TYPLFSYVNP DKSTLADVNG DGMLDFVSFV GTQSIVCLFM GNGFSNPIAT NLNAGNGKNL
     LDFNFGEVDG DGISDLVLFN KENHTIETYL SRGDGSFYYS PGFSFGGFST QEYTESNGIE
     RSDTVQISLQ DMNLDGISDV SIAFLSLDKT WGRIYYRYNN PRNSGEDQLL NVSNGAGQTS
     QVQYQLKNNH SGALQTGTGN YPDVPSMTPG FLVTQTRQDL SNGIVHTTNY SYTNERYIQG
     TRAISRSLGF ASIRETDVNT NFYKITDYFQ NDYRLAGVPQ STRNYNASNN LTGSTTQSGF
     SFPNPFGTEI AVVGTITTND YRNGTLVETS IQNFTYDSYG FTTSVIESLG SHTITNTSQV
     SNDVAGWRMG RVTRSRKNVD GTWVVDTQLG YTGDNLTSQT QFPTSASPLT TTFGYDSFGN
     VVSVTEPSGG VSFLTYDPVF NHFPVTKTNT LGHVTTTNYD FATGLETSST DPNGAITLTS
     YDGYGRKASV TYPGEGTANE TYTYSNTGEY NLTNLNNNEF VTKSIRDNVS GNVSTTRIFT
     DPLGNTIRSE GNTALSGINS IEDNYFDYTR GVLIQKSNEY YTSISPQFTT YQYNDPDGEL
     TTILEPSANG TIQTSITKTG FTETKTTTFP DGQTKTEVVT KNELGQVILK TVNGRTILTN
     YSPFGGISSV TDVGGLTTSF VYDSKGRRVS TQDPNSGTIS YSYDSLGRLY SQTDARGKTI
     TFTYDLLGRP LTQTTNGPEA PIQFTYDDAS VPFSRGRLTK VTDESGRTEF LFNQKGNEIQ
     KTKYVDDITA IFKTDYDSLN RPITETLPDG TKLHNFYSSN GTLSSITMDT ADGTSTGHTV
     VSYQGPYLDS NGVPSLRRTS GNGVTMEIGF EPLDKKPLSI VSKKPDGSVI GNTELTYDSK
     GYITKIEDKL NPNRTQNFTL DNLGRVTQAV GRYGTQNYTF SANGNLIQKG AYTLGYTDAS
     HSNAVTTATS ANTGVMTYGY DASGNMVSRN GDTLRYNSYG KLIEITPYAT SSSIRNVYDF
     QGNRVKSVSD ITLFSTYTLD DNYEIVREPG KPERHTLYVK GLQGDLVAQW TREDATLRIS
     GNESEESRFV LGDIFSSMIK PFCKDITGDC GDYWENRFES EFIGIFGYSK FFQSGVPTGL
     YKAFYFLLLL AVIYLVYPYF LKENLLLQNL GWKGGATPAL ILSLFVVTSL PGCGVLPGTG
     GKEGDPPWIL AMGANVAPGV PSIQNPGVGM TGGGSVGGMP VTGMYFYHPN HLGSITMITD
     GAGNPASGPE PGVSFVSYEP YGSIIRNDSY GPDIFRYKFT GQIEDKETGL YYYKSRFYEP
     TLGRFLQADS VIAPDSVNGM NRYMYVDGNP VSYRDPSGHI SGPDMMHMLN RIVGHAMGKD
     FNSKGLDKKL STNGISKGVN RFVHNATFVH NPTKLRGMRD STKGAILGYL MTGSFEGAFD
     GYLWGNAKDQ TKIDNKRKNY KWAFDLSDVV ISIAGFFITK NPYLIGYGIL RLGRAAEDLL
     DYSNTRRHIP NAAACAYNFM NNHYQENLGS LSTNNQFVEY QMLYNCAVGN TAGTSSRNTN
     GLGM
//