ID   N1W9G2_9LEPT            Unreviewed;       670 AA.
AC   N1W9G2;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Cyclic nucleotide-binding domain protein {ECO:0000313|EMBL:EMY71643.1};
GN   ORFNames=LEP1GSC199_0527 {ECO:0000313|EMBL:EMY71643.1};
OS   Leptospira vanthielii serovar Holland str. Waz Holland = ATCC 700522.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1218591 {ECO:0000313|EMBL:EMY71643.1, ECO:0000313|Proteomes:UP000012227};
RN   [1] {ECO:0000313|EMBL:EMY71643.1, ECO:0000313|Proteomes:UP000012227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Waz Holland {ECO:0000313|EMBL:EMY71643.1,
RC   ECO:0000313|Proteomes:UP000012227};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Galloway R.L., Vinetz J.M., Sutton G.G.,
RA   Nierman W.C., Fouts D.E.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMY71643.1}.
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DR   EMBL; AOGY02000011; EMY71643.1; -; Genomic_DNA.
DR   AlphaFoldDB; N1W9G2; -.
DR   STRING; 1218591.LEP1GSC199_0527; -.
DR   Proteomes; UP000012227; Unassembled WGS sequence.
DR   CDD; cd00038; CAP_ED; 2.
DR   CDD; cd07738; DdPDE5-like_MBL-fold; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR018488; cNMP-bd_CS.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR11635:SF168; CAMP PROTEIN KINASE REGULATORY CHAIN; 1.
DR   PANTHER; PTHR11635; CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN; 1.
DR   Pfam; PF00027; cNMP_binding; 2.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00100; cNMP; 2.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR   PROSITE; PS00888; CNMP_BINDING_1; 1.
DR   PROSITE; PS00889; CNMP_BINDING_2; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 2.
PE   4: Predicted;
FT   DOMAIN          426..527
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
FT   DOMAIN          556..670
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
SQ   SEQUENCE   670 AA;  76824 MW;  695F4E11952C41DD CRC64;
     MFVLPNKFFH VEKGISIAEL EFPIYFNFFF RGGKKTFIVC SPEQKEQLTI VLGESLMGPQ
     ELNLASEFID GTMSFGFPDI KAEMAHFRSY KTMEEVVEFV LFDENHKAQF GKITIEQLPS
     NEFLIVDGDK KIKTPGEVDF HVKYDIGKRL EEPFQPPIIG ITCLGPSHGF DPTDNTSGFI
     IWLNGQGIMV DPPVNSTEWL RESNVNPKFI NSIILTHCHA DHDAGTFQKI LEESKITIYA
     TATVMESFLK KYCSLTKIPR REITDLFDFI PVVIGRPTII NGGEFYFHYA LHSIPSVGFE
     FFFQDQSFYY TSDHLNDPEA FEEMYKKGVF PESRYQFLKD FPWDRNIIYH EAGVPPLHTK
     ISYLASLPEE VQKRITVYHI AAKDMPEGNH LTLAKFGIEN TLYPEITPPK HQEAFQLLEI
     LSQIDIFSGF PIEKAKEFLQ VVKEERFRRG EQIIKKGTHG DRFFIIASGN VRFEGLSGDH
     SAVKRYGTYE YFGEASLILD TARQADVYAE TDVLALTIEK TRFFQFIRGS KLHENLIKLN
     SIRETNTWKT LTESQTFRGL TSYQVTQLEL ILKLETVKKE ASLIEEGQTF HNAFIVRSGT
     VVVMQNHKTI RELGAGDFVG EIYSLTKNLP SNFSFIAWPG TELYVLSEED AIQYIKKNPG
     VYMKLNTVYN
//