ID N1Z9E2_9CLOT Unreviewed; 915 AA.
AC N1Z9E2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=VWA domain-containing protein {ECO:0000313|EMBL:NDO46746.1};
GN ORFNames=C820_000187 {ECO:0000313|EMBL:USF28813.1}, C820_01577
GN {ECO:0000313|EMBL:EMZ13672.1}, FMM67_07810
GN {ECO:0000313|EMBL:NDO46746.1};
OS Clostridium sp. MD294.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=97138 {ECO:0000313|EMBL:EMZ13672.1};
RN [1] {ECO:0000313|EMBL:EMZ13672.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ASF356 {ECO:0000313|EMBL:EMZ13672.1};
RX PubMed=24723722;
RA Wannemuehler M.J., Overstreet A.M., Ward D.V., Phillips G.J.;
RT "Draft genome sequences of the altered schaedler flora, a defined bacterial
RT community from gnotobiotic mice.";
RL Genome Announc. 2:e00287-e00214(2014).
RN [2] {ECO:0000313|EMBL:NDO46746.1, ECO:0000313|Proteomes:UP000462571}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ASF356 {ECO:0000313|Proteomes:UP000462571}, and MD294
RC {ECO:0000313|EMBL:NDO46746.1};
RA Elie C., Mathieu A., Saliou A., Darnaud M., Leulier F., Tamellini A.;
RT "Draft genome sequences of 15 bacterial species constituting the stable
RT defined intestinal microbiota of the GM15 gnotobiotic mouse model.";
RL Submitted (JUN-2019) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:USF28813.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ASF356 {ECO:0000313|EMBL:USF28813.1};
RA Proctor A., Parvinroo S., Richie T., Jia X., Lee S.T.M., Karp P.D.,
RA Paley S., Kostic A.D., Pierre J.F., Wannemuehler M.J., Phillips G.J.;
RT "Resources to Facilitate Use of the Altered Schaedler Flora (ASF) Mouse
RT Model to Study Microbiome Function.";
RL Submitted (MAY-2022) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AQFQ01000013; EMZ13672.1; -; Genomic_DNA.
DR EMBL; VIRC01000013; NDO46746.1; -; Genomic_DNA.
DR EMBL; CP097810; USF28813.1; -; Genomic_DNA.
DR RefSeq; WP_004036167.1; NZ_VIRC01000013.1.
DR AlphaFoldDB; N1Z9E2; -.
DR STRING; 97138.C820_01577; -.
DR PATRIC; fig|97138.3.peg.1586; -.
DR eggNOG; COG2304; Bacteria.
DR eggNOG; COG5426; Bacteria.
DR HOGENOM; CLU_007196_0_0_9; -.
DR OrthoDB; 9781333at2; -.
DR Proteomes; UP000012445; Chromosome.
DR Proteomes; UP000462571; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR37947; BLL2462 PROTEIN; 1.
DR PANTHER; PTHR37947:SF2; VWFA DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13519; VWA_2; 2.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000012445};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 822..840
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 408..579
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 878..915
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..895
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 915 AA; 101164 MW; 9004520C6D8C30DD CRC64;
MNVSVMKPYC ILFFVIVVLL LYVIAKKGNI KNTFSHRFFI FMRSIVALLL ILALCDISIQ
TTSQKVTTIF AVDLSDSTKQ SQQNIKTFLK QAESARSEKD NIGLLCFGGD AVLEQSPMSN
VPFPQNFLSY VQKNATNISS VLNLANAVIP EKTRKRIVLL SDGIETVGDG YAQSKLLQAQ
GITIDVFPLQ TKEQPEVQLS ALQVSNLINK NTEYDVTLQI SSNIDTQANV KLFKGNSLIA
NEQIAVVKGE SNIVFSDKTE NGGSILYRAE LSAQQDTISQ NNKAYAYCYI TDVAQILLIE
QYDSGNVWED FLQNSQVNVT KIAIENAPVI VEQLNQYDAV VLSDVSEESM PNGFLDALES
YVKTTGGGLL VTGGENSFAL GGYYKTKLEE ILPVEMELKT EGQNNSLGMV MVIDRSGSMD
GGEYGVSKIE MAKEACIRSL SSFMPGDCIG VIAFDDIAQW AVPFQTVQDN ITDIRMGIGS
IQPGGGTSIL PGLNAAYDVL KDANTKQKHI ILLTDGQAEQ SGYDSLLERM NTNGITLSTV
AVGTGADTAL LKRLSEQGGG RYYFTNEFSD LPEIFAKETL LAGKEYINNR TFYPKQKNAS
AIMADISSVA TLEGYIGTTA KPRADVVLES DKQEPILATW QYGLGRTAVW TSDVSGKWSK
NWLASQQGRQ ILQNSISWIM KKQSSKDITA SAVIEGEKSL LTVTMAYDES VSEVEGTVVS
NDNKTYNVIL NRTAPNVYVG TMDTIAEGGY ILNLQITNTK GETDSVNTGF AIAYPKEYDR
RNWGKGEVLL NRIAEATGGR VLTNGEEVFT QKPQAVSESK SLTNLFLILA LIVFLLDVFF
RRFYIVTQKL ENILKNLKKE KKQTVPQQTV QYNNFEKEMK QAQKRQQKKE KNQKEQQQNN
NMATQLAEAK KKRKR
//
