ID   N2A1I6_9FIRM            Unreviewed;       723 AA.
AC   N2A1I6;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=Sulfatase N-terminal domain-containing protein {ECO:0000259|Pfam:PF00884};
GN   ORFNames=C823_05111 {ECO:0000313|EMBL:EMZ20298.1};
OS   Eubacterium plexicaudatum ASF492.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Eubacterium.
OX   NCBI_TaxID=1235802 {ECO:0000313|EMBL:EMZ20298.1, ECO:0000313|Proteomes:UP000012589};
RN   [1] {ECO:0000313|EMBL:EMZ20298.1, ECO:0000313|Proteomes:UP000012589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ASF492 {ECO:0000313|EMBL:EMZ20298.1,
RC   ECO:0000313|Proteomes:UP000012589};
RX   PubMed=24723722;
RA   Wannemuehler M.J., Overstreet A.M., Ward D.V., Phillips G.J.;
RT   "Draft genome sequences of the altered schaedler flora, a defined bacterial
RT   community from gnotobiotic mice.";
RL   Genome Announc. 2:e00287-e00214(2014).
CC   -!- PATHWAY: Cell wall biogenesis; lipoteichoic acid biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00004936}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMZ20298.1}.
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DR   EMBL; AQFT01000148; EMZ20298.1; -; Genomic_DNA.
DR   AlphaFoldDB; N2A1I6; -.
DR   STRING; 1235802.C823_05111; -.
DR   PATRIC; fig|1235802.3.peg.5392; -.
DR   eggNOG; COG1368; Bacteria.
DR   HOGENOM; CLU_014385_3_2_9; -.
DR   OrthoDB; 243547at2; -.
DR   Proteomes; UP000012589; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd16015; LTA_synthase; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR000917; Sulfatase_N.
DR   PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR   PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR   Pfam; PF00884; Sulfatase; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000012589};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        96..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          277..517
FT                   /note="Sulfatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00884"
SQ   SEQUENCE   723 AA;  81486 MW;  04FE948A1629639A CRC64;
     MKKIFNNKWH RPTQASDSKK RDYSRQVALL NRYSLLFHAL LSCMLIFIIE ACSRRSIVDA
     AVFFSSHAFA FFFNALIIFF TLSVVYLFRR RTLMRIIISC IWLLLGIING CVLSQRVTPF
     GYTDLKCISD LLTMTNTQYF TKTQEICVII LLCVLVVFLI IFALKGPKFQ GHPHKIRAAC
     FCAGMGMVMS LATTMAHSSE QMASYFANIA QGYSDYGFVY GFSSSVMDRG MSKPKDYSES
     TIKAIKQSVA QAKEEASSYK IAQNDQVISD SAKKQQPNII CVLLESFMDP TEINYLKLSQ
     DPIPNFRALS DQFTSGYLSV PVVGAGTANS EFEVLTGMNL RFFGTGEYPY KTILKQTNCE
     SIASDLSATG YGTHVVHNNG GNFYSRANAF SQFGFDTFIS KEMMNIQEYT PLGSWPTDDI
     LIGETKKALD STPDQADFVY TITVQGHGNY PEEKIIENPE IKVSGAQTEE QNNQWEYYVN
     QIHEVDKFIK NLTDMLSERN EDTILVLFGD HLPTMGLADE DLKSGDIFKT KYATWNNFGL
     EKKDADLAAY QLLAYATDQA GIHEGTIFTY HQAENYRSDS ELYQNRLENL QYDILYGERY
     CYDGLDLYPA SDLQMGVDKT HIKYYRKNAD GSLSILGDHF TNWSRIYVND TKMSTTFVSD
     TELILSADDT SDLENGDVLK VCQVGSSSTI FRTTENTVSY YTADEPVAEA DSSLETTVSD
     SDE
//