ID N2B5B2_9HELI Unreviewed; 500 AA.
AC N2B5B2;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Ribonuclease Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE Short=RNase Y {ECO:0000256|HAMAP-Rule:MF_00335};
DE EC=3.1.-.- {ECO:0000256|HAMAP-Rule:MF_00335};
GN Name=rny {ECO:0000256|HAMAP-Rule:MF_00335};
GN ORFNames=C826_02336 {ECO:0000313|EMBL:EMZ36857.1};
OS Helicobacter bilis WiWa.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1235804 {ECO:0000313|EMBL:EMZ36857.1, ECO:0000313|Proteomes:UP000012527};
RN [1] {ECO:0000313|EMBL:EMZ36857.1, ECO:0000313|Proteomes:UP000012527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WiWa {ECO:0000313|EMBL:EMZ36857.1,
RC ECO:0000313|Proteomes:UP000012527};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Overstreet A.-M.C., Ramer-Tait A.E., Phillips G.J.,
RA Wannemuehler M.J., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Helicobacter bilis WiWa.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Endoribonuclease that initiates mRNA decay.
CC {ECO:0000256|HAMAP-Rule:MF_00335}.
CC -!- SIMILARITY: Belongs to the RNase Y family. {ECO:0000256|HAMAP-
CC Rule:MF_00335}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMZ36857.1}.
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DR EMBL; AQFW01000027; EMZ36857.1; -; Genomic_DNA.
DR RefSeq; WP_004084947.1; NZ_KB822507.1.
DR AlphaFoldDB; N2B5B2; -.
DR GeneID; 60656013; -.
DR PATRIC; fig|1235804.3.peg.2563; -.
DR HOGENOM; CLU_028328_1_0_7; -.
DR Proteomes; UP000012527; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004521; F:RNA endonuclease activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd00077; HDc; 1.
DR CDD; cd22431; KH-I_RNaseY; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR HAMAP; MF_00335; RNase_Y; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR017705; Ribonuclease_Y.
DR InterPro; IPR022711; RNase_Y_N.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR03319; RNase_Y; 1.
DR PANTHER; PTHR12826; RIBONUCLEASE Y; 1.
DR PANTHER; PTHR12826:SF15; RIBONUCLEASE Y; 1.
DR Pfam; PF01966; HD; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF12072; RNase_Y_N; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000256|HAMAP-
KW Rule:MF_00335};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|HAMAP-Rule:MF_00335};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722, ECO:0000256|HAMAP-Rule:MF_00335};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|HAMAP-
KW Rule:MF_00335}.
FT DOMAIN 317..410
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT COILED 36..117
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 500 AA; 56495 MW; 6FBCEC2B8AFBF55B CRC64;
MTSIVLLSCG ATAICVAFIT FFVARKFSYA KMLLCIEQNN AKIKALETEI EQLLHNKHVK
MQEEEEQFNK KLAKRKNELE KIIQEHEESN KIINHAKQEV LRQKEEQAKI LERCQEEKIK
LSSLLQDYTA LTKEEGKKIL LKNLEDELIQ ERASLIRRYE TEAKAEAKRK ANYIIAQATT
RFAGEFVSDR LVNNVRLVND EMKGKIIGKE GRNIKAFEMV CGVNLIIDDT PNEISLSSFS
LYRRALATRT LEILMQDGRI HPSRIEEVYE KVKAQAEEQL YQEGDEILLE LGIGYVESEL
KKLIGKLKYR ASFGQNALQH SLEVARLAGI IAGELGGNVK LARRAGLLHD IGKALTDEQG
GSHVDLGADI CLRYNEDPVV INAIYAHHGH EESKSIECSA VCTADALSAA RPGARNEANE
SYINRVRDLE KIAMEKFGVK QAYAVYAGRE IRVIVRADLV NDIESVVLSR EIANEIKQQL
QYPGEIKVNV IREMRAVAYA
//
