ID N2BMY3_9HELI Unreviewed; 1543 AA.
AC N2BMY3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=C826_01727 {ECO:0000313|EMBL:EMZ38214.1};
OS Helicobacter bilis WiWa.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1235804 {ECO:0000313|EMBL:EMZ38214.1, ECO:0000313|Proteomes:UP000012527};
RN [1] {ECO:0000313|EMBL:EMZ38214.1, ECO:0000313|Proteomes:UP000012527}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WiWa {ECO:0000313|EMBL:EMZ38214.1,
RC ECO:0000313|Proteomes:UP000012527};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Overstreet A.-M.C., Ramer-Tait A.E., Phillips G.J.,
RA Wannemuehler M.J., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Helicobacter bilis WiWa.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMZ38214.1}.
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DR EMBL; AQFW01000015; EMZ38214.1; -; Genomic_DNA.
DR PATRIC; fig|1235804.3.peg.1885; -.
DR HOGENOM; CLU_003936_0_0_7; -.
DR Proteomes; UP000012527; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR025199; FtsK_4TM.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF13491; FtsK_4TM; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1224..1410
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 245..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 931..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 1241..1248
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1543 AA; 173789 MW; 3DD519D91A0833A5 CRC64;
MLYLWLATIF GYTPPDAALS GAAVSNSFFK IGGFGNSFAN FNRGMFGYLA YIYLPLLLLP
IYRFHDDTSY SFRKIQLSFA YLLLFIGLLL LQSLVFHSGQ FGNYLQEVLT PYIGLFGVAI
LTFICISTAL LLIAERTATF ILGYLGGSLQ MAYSATSNFA KRAFQQLKSK YTDFKLDSIQ
REKRKIVNQE LSEKATTTKS KYIDREPLLE TALDEYPRTN TNNGYTDTNM QNLARNENLV
HNKDMQSSNT QTTNKQEAPQ DSKEFSIQVK PSNNINTTQT LSYQQYDDSN ISPITHTPRT
QMKNNDEELL RRFQKANLYP KQKDQQTFHT DSPMTFRLKQ EMGEANPLES FAKTQQPKIL
PTIDDWQTTD MPPREVKTTN LIKPKAQGRE QPKTETFSVK EGITTQDNAT PTTPKILETF
KEDSTAQIQP KTITQESPTI RIKESEIKDS TNTHLNTPKL EINPNQQHTE QKKTIKIQAI
NTPKIEQMPA QANYKTLDMS FTQKEYKTTN PSINESTITL SQPNSTDFNQ TTQETTNFNQ
TQITESNLNV AQTLESQHID YTSQQYDLNT QTLQQNTLDS QPSELVLQQD IPETNNLQDS
PFITPLESTQ NNIDYTETTT IIIPPLLDSN EDSRNDFREE FRGDFNTQDL IIQDSISKDS
NINNSQDSII IESIPQESTH SLDSTESNHT LQDDIREEIK EIFIEPLESL EAHTQSISQS
SQIDSKQTDF ISTESNMLNS NKLDTIHIDS IPTESNVSNL NQIESSYTDS IDLLKTNSSV
ESKQAESIPQ DSILIETTQI ESNIQTQHTQ DFEIKEITQE NTEHVENIES SITDSNLTKE
LKNKDYLQQS TMQDLEQNHT GSKIAQEITP TQQNITINTY TPQMTHSHFP THTNPTNYFT
GMPTHSQAQP MNYIFDSTTH TQTSTIKPNV ESSTIESNNQ QFHNTESNPA QPNNTQSNEI
ENNTTQHNLA QSNNIESTHT NPTTQPIKIK LYDDKQTSRT ITHKDIIQNN ISTQTKDTAH
SFTIKDSSPH IESKTTQITE SNDNENREDM IIRQIAQKKE EARQESNMLI ANHDTNIAHL
AQSTNLPPFI LPPLKLLQEP IAQDSIQDIE LDSKIDKMLQ IFNAHKIRGD IIATLTGPVV
TTFEFRPETH VKVSKILSHK NDLARILKAK SIRIQAPIPG KDVIGIQIPN SKVETIYLRE
ILHSQAFLDS KDPLTIALGK DISGTPIVAN LAKLPHLLVA GTTGSGKSVG VNAIILSLLY
RNDPDNLKLM MIDPKQVEFA PYEDLPHLIT PIINAPNKAI KALQVATIEM DKRYELFSQI
KVKNIASYNE KVSIKMPNFV IIIDELADLM ITGGKEAEAF IARIAQMGRA AGMHLIIATQ
RSSVNVITGH IKANLPSRIS YRVGSRIDSK VILDEMGAED LLGNGDGLFT TTNGLMRIHA
PWVSEQEVEH IVDFIKAQRE PQYDESFLSE TKPGAVSGDK FSGDGSLLDK AKEVMMQDNK
TSISYLQRKL GIGYNKSASL VEALEKEGFL SPPNSKGERN ILV
//
