ID   N4U9S0_FUSC1            Unreviewed;       731 AA.
AC   N4U9S0;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Hormone-sensitive lipase {ECO:0000313|EMBL:ENH72573.1};
GN   ORFNames=FOC1_g10013230 {ECO:0000313|EMBL:ENH72573.1};
OS   Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium oxysporum species complex.
OX   NCBI_TaxID=1229664 {ECO:0000313|EMBL:ENH72573.1, ECO:0000313|Proteomes:UP000016928};
RN   [1] {ECO:0000313|Proteomes:UP000016928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RA   Fang X., Huang J.;
RT   "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT   banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000016928}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RX   PubMed=24743270;
RA   Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA   Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA   Fang X., Peng M., Huang J.;
RT   "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT   oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL   PLoS ONE 9:E95543-E95543(2014).
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DR   EMBL; KB730093; ENH72573.1; -; Genomic_DNA.
DR   AlphaFoldDB; N4U9S0; -.
DR   STRING; 1229664.N4U9S0; -.
DR   VEuPathDB; FungiDB:FOC1_g10013230; -.
DR   HOGENOM; CLU_003590_1_0_1; -.
DR   OMA; NMYDATY; -.
DR   Proteomes; UP000016928; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013094; AB_hydrolase_3.
DR   PANTHER; PTHR23025:SF3; HORMONE-SENSITIVE LIPASE; 1.
DR   PANTHER; PTHR23025; TRIACYLGLYCEROL LIPASE; 1.
DR   Pfam; PF07859; Abhydrolase_3; 2.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016928}.
FT   DOMAIN          220..369
FT                   /note="Alpha/beta hydrolase fold-3"
FT                   /evidence="ECO:0000259|Pfam:PF07859"
FT   DOMAIN          451..547
FT                   /note="Alpha/beta hydrolase fold-3"
FT                   /evidence="ECO:0000259|Pfam:PF07859"
FT   REGION          360..399
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          411..454
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          602..710
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        435..450
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        619..638
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        639..681
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   731 AA;  82579 MW;  0AB69AB1FC9EA3FB CRC64;
     MIDHVLGRPS VKSRRLQVLA VLTFWSAYLV KGHKHGPPGA QLLSRLFSKR LTAWQTVVIT
     MIYLYAARNF STLVGLASPE PMANMYDATY YRATWVLTAL DAGFWTAMKI KTKWLRDMAS
     IVFSLFYLVA AEKADEKVRK VRGMITVEHL RVSWNKGTSP YLSFFQGLMR PRFMRWPPRQ
     IRIPRPADSD YKEPVLAWLY YDGPLSDLHR HDRLILDIPG GGFVAMDPRC NDDKLFSWAA
     KSALPILSLD YKKAPEFPYP YALNECFDVY RTIVNTKGRC IGLPGTEVPR IIVTGDSAGG
     NLAVASTLMI METRHPAFRR PGQTELPAPD GLVCFYPALD MNIGNWMTDE QMSLIKDRKM
     RKTNRRIMRR KSMQYNELVG TPHHSDDEED GSPPPHTKLS ALTTKEALIA ASQGPRSPHP
     EFSHVGPRSL SLPKDASETN EKKSSHHPEP MKTRLATSSM ISYFNDRVLT PEMMRAMIIL
     YIGAHNRPDF SQDYLLSPVL APEALLVDFP KTYFMTGERD PLVDDTVIFA GRLRRAKEAA
     FVQEQSGRHQ NAEVMLIPGT SHGFMQFPTV YPPAWRHFER CIDWFDQLFD HAEVMRVRKD
     RQARAARSQT NGFGINGDGR HHMRTESSED DRPLEISMTK MNQRRSSNQT TPQQSPDLNG
     GSESGDTTPR AHTNGTSLSN GDKNAKKRKS VGLSKSKNRN KSLVKLKSSD DLLGRRMQGL
     ASGLTGMGDD D
//