ID N4UIJ0_FUSC1 Unreviewed; 843 AA.
AC N4UIJ0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=FOC1_g10001604 {ECO:0000313|EMBL:ENH75588.1};
OS Fusarium oxysporum f. sp. cubense (strain race 1) (Panama disease fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium oxysporum species complex.
OX NCBI_TaxID=1229664 {ECO:0000313|EMBL:ENH75588.1, ECO:0000313|Proteomes:UP000016928};
RN [1] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RA Fang X., Huang J.;
RT "Genome sequencing and comparative transcriptomics of race 1 and race 4 of
RT banana pathogen: Fusarium oxysporum f. sp. cubense.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000016928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=race 1 {ECO:0000313|Proteomes:UP000016928};
RX PubMed=24743270;
RA Guo L., Han L., Yang L., Zeng H., Fan D., Zhu Y., Feng Y., Wang G.,
RA Peng C., Jiang X., Zhou D., Ni P., Liang C., Liu L., Wang J., Mao C.,
RA Fang X., Peng M., Huang J.;
RT "Genome and Transcriptome Analysis of the Fungal Pathogen Fusarium
RT oxysporum f. sp. cubense Causing Banana Vascular Wilt Disease.";
RL PLoS ONE 9:E95543-E95543(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.49;
CC Evidence={ECO:0000256|ARBA:ARBA00024557};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; KB729964; ENH75588.1; -; Genomic_DNA.
DR AlphaFoldDB; N4UIJ0; -.
DR STRING; 1229664.N4UIJ0; -.
DR VEuPathDB; FungiDB:FOC1_g10001604; -.
DR HOGENOM; CLU_017238_1_0_1; -.
DR OMA; CKAYAMA; -.
DR Proteomes; UP000016928; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR42648; TRANSPOSASE, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR42648:SF11; TRANSPOSON TY4-P GAG-POL POLYPROTEIN; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016928};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464};
KW Transposition {ECO:0000256|ARBA:ARBA00022578}.
FT DOMAIN 619..784
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 45..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..324
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 96556 MW; 320FAB575947992D CRC64;
MSTNNLSSKK VTLQTFEDWG RWDEEFQTKA MSLHLWEFID PESDETLMQR PERPNVGAYS
RRVPPRPADP DLAPSGVQTR RGGQSKTVDP HHHARNVSEL TAEDKATFTF EWRVYEQDHR
EYKEQEANCE KLKAWVTETV DYGLRQSSCR AIWDLRTWYT NLKTSVGATQ REQQIAARRN
YQAAITPLAK IPKDFANWIT AWEMATNHAL VMKTGGVDDP NTWFDDLAKA IQPVLGNWVT
IYTGIYKDKL EGKTLTIGEV AKDLRKEVER QTLIQPQKGH RVTKGAFGPT FAGESSTLSQ
TRAGTPEREI RPRNHGEASG RKRKARQGSP AARKRVAPSA DSDSRCQACE GNHALSSCYY
VFPEKAPEYF KSRKLVCDAV EHRLKTDQHL KTEVDCIKNF VIASFNLMLS TTHYPLVNSA
ILDSGSTIHI FNNIDRFSKF RHAEPGDFVL AGEGRVPVQG YGNVVIRAHG PRGSKFLRLN
DVVFCENFPC NLVSLRQLRK RGYWWDNRPG YNCLREWNGA LVCNLVDQHD QFVIEDLPPD
ISKTSFITRQ HKLNSWTDRT SKVDARKWHL RLGHPGPQAL EHLVNTTRGT RIKGPTTVEC
DDCAISKISR QISRRPREVG HTPGERLAVD FHDLVRDWGG RTSVMLITDR WSGMIWDYYL
ADRHTGTLIT ALKDLFGLLE RQYQLKPKIL ECDNEIPNAG TVFEFLRTLH IKVEPSAPYT
QAQNGGAEVS GKIIKNKARA MRAGARLPED LWVEIYRAAV YLYNRTPRYT HNWRTPYDKF
HTFLAHRDGI VVEDRKPYQA HLRVYGCKAF AMTREAKTKQ QKKHRLNPRA WIGFLVGYQS
TNI
//
