ID N4V1E8_COLOR Unreviewed; 1307 AA.
AC N4V1E8;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=DNA repair protein RAD50 {ECO:0000313|EMBL:TDZ20328.1};
GN Name=RAD50 {ECO:0000313|EMBL:TDZ20328.1};
GN ORFNames=Cob_v006782 {ECO:0000313|EMBL:TDZ20328.1};
OS Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS
OS 414 / MAFF 240422) (Cucumber anthracnose fungus) (Colletotrichum
OS lagenarium).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum orbiculare species complex.
OX NCBI_TaxID=1213857 {ECO:0000313|EMBL:TDZ20328.1, ECO:0000313|Proteomes:UP000014480};
RN [1] {ECO:0000313|Proteomes:UP000014480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=23252678; DOI=10.1111/nph.12085;
RA Gan P., Ikeda K., Irieda H., Narusaka M., O'Connell R.J., Narusaka Y.,
RA Takano Y., Kubo Y., Shirasu K.;
RT "Comparative genomic and transcriptomic analyses reveal the hemibiotrophic
RT stage shift of Colletotrichum fungi.";
RL New Phytol. 197:1236-1249(2013).
RN [2] {ECO:0000313|Proteomes:UP000014480}
RP GENOME REANNOTATION.
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=30893003; DOI=10.1094/MPMI-12-18-0352-A;
RA Gan P., Tsushima A., Narusaka M., Narusaka Y., Takano Y., Kubo Y.,
RA Shirasu K.;
RT "Genome sequence resources for four phytopathogenic fungi from the
RT Colletotrichum orbiculare species complex.";
RL Mol. Plant Microbe Interact. 32:1088-1090(2019).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC {ECO:0000256|ARBA:ARBA00009439}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDZ20328.1}.
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DR EMBL; AMCV02000017; TDZ20328.1; -; Genomic_DNA.
DR STRING; 1213857.N4V1E8; -.
DR EnsemblFungi; ENH77427; ENH77427; Cob_13439.
DR eggNOG; KOG0962; Eukaryota.
DR HOGENOM; CLU_006184_0_0_1; -.
DR OrthoDB; 5477220at2759; -.
DR Proteomes; UP000014480; Unassembled WGS sequence.
DR GO; GO:0030870; C:Mre11 complex; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR InterPro; IPR004584; Rad50_eukaryotes.
DR NCBIfam; TIGR00606; rad50; 1.
DR PANTHER; PTHR18867:SF12; DNA REPAIR PROTEIN RAD50; 1.
DR PANTHER; PTHR18867; RAD50; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000014480};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 6..239
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
SQ SEQUENCE 1307 AA; 150118 MW; C998FCDC05CE56D1 CRC64;
MSKIDKLSVQ GIRSFGGSRE TISFYTPLTL IVGYNGSGKT TIIECLKYAT TGEQPPNSKG
GAFVHDPKLV GEKEVLAQVK LAFSSTGGLK YVATRSLQLT VKKTTRSLKS LEGSLACNNN
GERTVTSSRV AQMDELIPRE LGVSRAILDY VIFCHQDESL WPMSEPAALK KQFDQIFEAM
RYTKAIDNLK LLRKKQGEEL SKLKIFEEQD RINKEKGDRA EKRSMALEKE IEQAREKCEA
LSTEMDEMQE EIRLKHEEAN RFLNIVNDLK FKEDQLKYRE GAIADLKMTL EELPEDDDYL
QDALEQYEER MSRFQEEADE NKAQYAELQQ DLNKSRRDLS AKLAEQGKHQ SDKDKYERQL
QTRVELVHQA AELHGFRGFD GDLKDSQVHA FNERIQKLLA DKKRELDRVQ KENARELDQA
TGVITELEGR KATTTQNRVF AKQRLGAIEK RISVLQMDIN RLDIDEGAKA ILDSQFEDVE
ARLKQANEVL ASADLDNQLQ QENEKLWQLE NETEKLGREL IECTRLASER AQLDLRKKEL
SDRNRKLETL TSTWRPKLDT HIGSGWKTDT LESQYHDALK RQNKLLAEAR QKRDAARDKQ
QKVDYRLKSA KEVGQKKTTE AFRCRDAVVE ALRTVRDGAN IEDYEEEVKM HEDDVETYTT
DISLLDALAD YYRSCQKTLQ AQNKCRLCDR QFDEKQNVSK SRFSDKLVKF LDPNKKEKAE
EDLANSSEIL NSLRKVKSQY ETYQRLMEEI PGVKEECSSL EGECETLDRQ LEEHDAAVTA
EEGKLADIES LNKTVINITQ TLKDIKDSEA QVDRIMSQQS SSVASRSADE IHELQASCNE
QIRSMKNKIA KTTADRQRMK DQLNALELEK SELKNKLSKA LNQLERKKDF QNQIQTLRDD
QTHQRELISK ADQDLESIEP EIAEARSIRN DTLQRGRAKE QGIAEERDRV ADSVTELKMA
ESDIQDYIDR GGPSNLAANQ RAIGSLEKAI AALEKDISEL TLRTNKLRQD IENGDRKKQN
IGNNLKYRQN LRQLEILRRE IRELQSRDAE DDYRTLSAEA KQLENRHNRL VAERGSIMGQ
MKTKDEELGR LIAEWEQEYK DASRKYRESH IKVETTKAAI EDLGRYGTAL DNAIMSYHGL
KMEEVNRIAG ELWQSTYQGT DIDTILIRSD NENATAGRRS YNYRVCMVKQ DTEMDMRGRC
SAGQKVLASI IIRLALAESF GVNCGLIALD EPTTNLDKDN IKSLAESLHS IIKARQAQSN
FQLIVITHDE EFLRHMRCSD FCDSFFRVRR DDKQNSVISK ESITRVV
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