ID N4V9W5_COLOR Unreviewed; 469 AA.
AC N4V9W5;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=cellulase {ECO:0000256|ARBA:ARBA00012601};
DE EC=3.2.1.4 {ECO:0000256|ARBA:ARBA00012601};
GN Name=egl2 {ECO:0000313|EMBL:TDZ23788.1};
GN ORFNames=Cob_v003270 {ECO:0000313|EMBL:TDZ23788.1};
OS Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS
OS 414 / MAFF 240422) (Cucumber anthracnose fungus) (Colletotrichum
OS lagenarium).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum orbiculare species complex.
OX NCBI_TaxID=1213857 {ECO:0000313|EMBL:TDZ23788.1, ECO:0000313|Proteomes:UP000014480};
RN [1] {ECO:0000313|Proteomes:UP000014480}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=23252678; DOI=10.1111/nph.12085;
RA Gan P., Ikeda K., Irieda H., Narusaka M., O'Connell R.J., Narusaka Y.,
RA Takano Y., Kubo Y., Shirasu K.;
RT "Comparative genomic and transcriptomic analyses reveal the hemibiotrophic
RT stage shift of Colletotrichum fungi.";
RL New Phytol. 197:1236-1249(2013).
RN [2] {ECO:0000313|Proteomes:UP000014480}
RP GENOME REANNOTATION.
RC STRAIN=104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF 240422
RC {ECO:0000313|Proteomes:UP000014480};
RX PubMed=30893003; DOI=10.1094/MPMI-12-18-0352-A;
RA Gan P., Tsushima A., Narusaka M., Narusaka Y., Takano Y., Kubo Y.,
RA Shirasu K.;
RT "Genome sequence resources for four phytopathogenic fungi from the
RT Colletotrichum orbiculare species complex.";
RL Mol. Plant Microbe Interact. 32:1088-1090(2019).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000966};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641, ECO:0000256|RuleBase:RU361153}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:TDZ23788.1}.
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DR EMBL; AMCV02000005; TDZ23788.1; -; Genomic_DNA.
DR AlphaFoldDB; N4V9W5; -.
DR STRING; 1213857.N4V9W5; -.
DR EnsemblFungi; ENH77811; ENH77811; Cob_12739.
DR eggNOG; ENOG502QXN4; Eukaryota.
DR HOGENOM; CLU_029718_1_2_1; -.
DR OrthoDB; 1638835at2759; -.
DR Proteomes; UP000014480; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR018087; Glyco_hydro_5_CS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR34142:SF5; CBM1 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR34142; ENDO-BETA-1,4-GLUCANASE A; 1.
DR Pfam; PF00150; Cellulase; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW Hydrolase {ECO:0000256|RuleBase:RU361153};
KW Reference proteome {ECO:0000313|Proteomes:UP000014480};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 56..306
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
SQ SEQUENCE 469 AA; 48864 MW; E460F49F94856A96 CRC64;
MVRKTVTVLG LAAAAWAKVQ FLGVAISGGD FGCETNGNCP IGRVQLPLSS LGGGDGEGQM
NHFVSNDNLN MFRLPIGWQF LVNNQLGGPL DANNLGRYDQ VMQKCLATGA HCIIDIHNFA
RWNGGVVGQG GPTDDDFVSL WTQLAQKYKS SDKVVFELMN EPHDLDVKIW AATCQKVVAA
IRQAGATAHM ILLPGTNFNS AEHLVSSGSA EALAAITNPD GTTDGLIIDV HKYLDEDNSG
THKTCTTDNV ESFRTVAEFL RAKGRKGLVS ETGASSDSSC FTAFCAQNKF INENSDVFIG
LVGWAAGSFG TDYVLSLTPK KSGGGGYADN ELMKQCVLGT WDTEQNVTAP ATTPSQPAVS
AAPSKAPPTS VRPSRSPSVL PSQVPSAEPT APLGPTSSEE GILPPTSAVV IPSTLVVDTA
TPTPPVPTGR RNGTATPSAP SPPTAGGARV KVVGGLLGLG LGLVMTIFM
//
