ID N6T3L3_DENPD Unreviewed; 451 AA.
AC N6T3L3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
DE Flags: Fragment;
GN Name=109543364 {ECO:0000313|EnsemblMetazoa:ENN72188};
GN ORFNames=YQE_11148 {ECO:0000313|EMBL:ENN72188.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ENN72188.1};
RN [1] {ECO:0000313|EMBL:ENN72188.1, ECO:0000313|Proteomes:UP000019118}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
RN [2] {ECO:0000313|EnsemblMetazoa:ENN72188}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2017) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|RuleBase:RU361203};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|RuleBase:RU361203}.
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DR EMBL; APGK01053843; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; APGK01053844; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; APGK01053845; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB741237; ENN72188.1; -; Genomic_DNA.
DR RefSeq; XP_019768604.1; XM_019913045.1.
DR AlphaFoldDB; N6T3L3; -.
DR EnsemblMetazoa; ENN72188; ENN72188; YQE_11148.
DR GeneID; 109543364; -.
DR KEGG; dpa:109543364; -.
DR HOGENOM; CLU_013387_5_0_1; -.
DR OMA; QYIHRVW; -.
DR OrthoDB; 203742at2759; -.
DR Proteomes; UP000019118; Unassembled WGS sequence.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR45867:SF3; ACID PHOSPHATASE TYPE 7; 1.
DR PANTHER; PTHR45867; PURPLE ACID PHOSPHATASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|RuleBase:RU361203};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 18..451
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5010896344"
FT DOMAIN 26..117
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 128..332
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 357..419
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ENN72188.1"
SQ SEQUENCE 451 AA; 51966 MW; 9D275268C43D238C CRC64;
MFYVLLVASS FLACGLAQKS PLYMQPQQVH IAFGDNIHQI VVTWSTYNPT DDSIVEYGIG
GLINTATGQS RLFVDGGPEK HSQYIHRVVL SDLAPDSRYE YHCGGSDGWS DLFWFKTLPS
GDDWSPHLVI YGDMGNDNAQ SLTRLQEETQ RGLYDAVLHI GDFAYDMDSD NGYVGDEFMR
QIEPIAAYLP YMTCPGNHEE AYNFSNYKAR FSMPGAPDSV MYSFDIGPMH IISISTELYY
FLNFGLKSLV FQFEWLKNDL IQANLPENRE KHPWIVVVGH RPMYCSNLNP DDCTHHETLT
RVGLPFLHMF GLENLLYNYG VDLEIWAHEH SYERLWPIYD YKVYNGSYEA PYTNPKAPVH
FVTGSAGCVE GRENFTTTRP YWSAFISRDY GYTRLRAFNR THLYWEQVSD DKAGEIIDSV
WLIKDSHGLY PHSKMDWESI EQMRLKTFNN V
//
