ID N6TKY0_DENPD Unreviewed; 410 AA.
AC N6TKY0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Solute carrier family 25 member 46 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN Name=109532898 {ECO:0000313|EnsemblMetazoa:ENN81079};
GN ORFNames=D910_02615 {ECO:0000313|EMBL:ERL85193.1}, YQE_02448
GN {ECO:0000313|EMBL:ENN81079.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ENN81079.1};
RN [1] {ECO:0000313|Proteomes:UP000019118, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
RN [2] {ECO:0000313|EnsemblMetazoa:ENN81079}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC outer membrane {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004374}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; APGK01020335; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB740193; ENN81079.1; -; Genomic_DNA.
DR EMBL; KB631669; ERL85193.1; -; Genomic_DNA.
DR RefSeq; XP_019753586.1; XM_019898027.1.
DR RefSeq; XP_019753587.1; XM_019898028.1.
DR AlphaFoldDB; N6TKY0; -.
DR EnsemblMetazoa; ENN81079; ENN81079; YQE_02448.
DR GeneID; 109532898; -.
DR KEGG; dpa:109532898; -.
DR HOGENOM; CLU_047010_0_0_1; -.
DR OMA; RQCQVNH; -.
DR OrthoDB; 2874292at2759; -.
DR Proteomes; UP000019118; Unassembled WGS sequence.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0090149; P:mitochondrial membrane fission; IEA:InterPro.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR InterPro; IPR039158; SLC25A46.
DR PANTHER; PTHR21252:SF2; MITOCHONDRIAL OUTER MEMBRANE PROTEIN SLC25A46; 1.
DR PANTHER; PTHR21252; TB1 PROTEIN-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 1.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transport {ECO:0000256|RuleBase:RU000488}.
FT REPEAT 273..375
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REGION 383..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ENN81079.1"
SQ SEQUENCE 410 AA; 45836 MW; BE63BCA882C544CA CRC64;
MDSGDWSHRY GDYNGRENYL DAPDLTRRLP VHDEYYLNRE HLPQYTSPKP YQSPEEVSVK
RYIGSGVAFA SLITENLLSH PFLVLRRQCQ VNHSSRIYHL LPFTLLPPVC HLQQHQGLTT
LWKGLGSVLL VRGMSLGVED LLSKLTPWPK EISPHSSLKQ FFQHTMLKCV SLAVVTPFYS
ASFVETVQSE IASERPGTLD VFREGFIRLL TWGAPAKGRM LPIWALILPT ITLGLAKYLF
SMMVKGVATW VLNIRQNNKW QKTGTIPKDS NPAMEDINLS ASLIATISSD IVFYPCETIV
HRLHLQGTRT IVDNLGDGRS VLPILTNYSG ALDCYSKCIL TEGTTGLYKG FGALILQYVA
HIALIKISRF VLTEVGALLK KPEPKLPNPV DDSPPAISNV TNPPKSYLLP
//
