ID N6TSJ4_DENPD Unreviewed; 1213 AA.
AC N6TSJ4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
DE Flags: Fragment;
GN ORFNames=D910_02009 {ECO:0000313|EMBL:ERL84580.1}, YQE_02575
GN {ECO:0000313|EMBL:ENN81013.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ENN81013.1};
RN [1] {ECO:0000313|Proteomes:UP000019118, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
RN [2] {ECO:0000313|EnsemblMetazoa:ENN81013}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2017) to UniProtKB.
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DR EMBL; APGK01020666; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB740229; ENN81013.1; -; Genomic_DNA.
DR EMBL; KB631604; ERL84580.1; -; Genomic_DNA.
DR AlphaFoldDB; N6TSJ4; -.
DR STRING; 77166.N6TSJ4; -.
DR EnsemblMetazoa; ENN81013; ENN81013; YQE_02575.
DR HOGENOM; CLU_269562_0_0_1; -.
DR OMA; DKKSPFQ; -.
DR Proteomes; UP000019118; Unassembled WGS sequence.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR12156:SF5; KINESIN-LIKE PROTEIN UNC-104; 1.
DR PANTHER; PTHR12156; PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742}.
FT DOMAIN 1102..1204
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 107..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 369..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 533..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 834..869
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 983..1045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 320..368
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 626..794
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 369..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..581
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..601
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 983..1009
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1016..1037
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ENN81013.1"
SQ SEQUENCE 1213 AA; 138657 MW; 4D7947BF9DFD54AB CRC64;
RVTLGSGSGV DIPVQGTGVS PLHCHIENSE GVVTLYPLSD NLSIDGLKVQ GPTRLSQGVM
LTIGRSNYLR FNHPAEAKLM KSVLPNPRIS MAPITFEPAD MNYRESKLNK KPPVVPRKSP
RESLSDSGSE EPPSSIMTKV SKFEYLAAQN LKKAYSPKVF TSNVPTMNVP VKDVLGKDID
SLSLRKSLPQ SAVNYVELNT NEKQQNKIPG QTIFTKQKQP AYVNVTVNET RNINNRVIIY
ENGCIPKSSN VNFDHNDLNN KTATKNVNVN RANAPSPSFS RNPAQFYRSV TPSPISNNMK
IEHRRSGSVG ELPANYVEDL DSLASRKHEA EIRRNQAQRD RIKEQELEKA EKQRLEEILN
MCAEYERQCQ TQGEKSKPPT PNRIITNGSL PRDKRHLGSP FGSPPPSPLE ILHNELLKQS
NHNYENVPMN FHKPEPPYRG PYENVEIRQA ATKDGDCGGT YENVSLQTTG SYPSSPRTRI
KTFVAANKDG NLRSVEDSID SKFAVFETER KLIKEAERVL RQNLHNSKEI TDDNLDLGHL
EPRKSTPTKF IYPMEGEETS AKDRQSSECR MSLESTKKGE DSTTADSVSF DSSQEYNRRL
SASQSPEERK RWEQLRKEKR DILAVIARIR RQMNEIEIQE EELHREIELE KALINGEFKS
KELELEKIES KKQKLQKRAQ RIEDNMRDCQ IKQEEDQEEC KKKLQFAQDA MDRMEEKLKA
TEKTSSDYEA VFEEYLQAQE QLDNERKNFE DLEFHHLEEE ADWLASREEL QREISDLSNR
IEHVKGNLKD LDSQKQKTSK TNSNEYKTIE KQKLECMVRL EEIRDRLKSI DTELMFSNQE
SDQEASSESD DSDKSKERPQ SNTAPKITNM SCSMIVSNHN SSQLSEYNMS QSFNEKLIHE
TFILEDGMAK KFPSQDDIDR ISKVTSDAPI IEEGRQSLGR KAIESLKEIE RNRHLHLCQQ
GSQVIEQERQ RVLALKQRVQ EEVKSQWAQQ RQDSVISSGS DSFRNSGSDP APKPDSKVAN
GDENRKSKED EVDNSPRPLS EISEMSVEVG GTLGKKRIKP ISDKQRPLTR YLPIRGSDLD
LRNHIETAGH QVVLCPHVII NSNTCRGFLH KKGSKLNGWS RRWFVFDRNK HTLTYYTDKS
EKKARGGAYF QAIEEVYLDH LNTVKSPNPQ LTFIVKTHER LYHLMAPSPE AMRIWVDVIF
TGAEGYREFE HGT
//
