ID N6TXL5_DENPD Unreviewed; 690 AA.
AC N6TXL5;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
DE Flags: Fragment;
GN Name=109542300 {ECO:0000313|EnsemblMetazoa:ENN73106};
GN ORFNames=YQE_10247 {ECO:0000313|EMBL:ENN73106.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ENN73106.1};
RN [1] {ECO:0000313|EMBL:ENN73106.1, ECO:0000313|Proteomes:UP000019118}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
RN [2] {ECO:0000313|EnsemblMetazoa:ENN73106}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2017) to UniProtKB.
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC ECO:0000256|RuleBase:RU365057}.
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DR EMBL; APGK01050956; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB741180; ENN73106.1; -; Genomic_DNA.
DR RefSeq; XP_019767035.1; XM_019911476.1.
DR AlphaFoldDB; N6TXL5; -.
DR EnsemblMetazoa; ENN73106; ENN73106; YQE_10247.
DR GeneID; 109542300; -.
DR KEGG; dpa:109542300; -.
DR HOGENOM; CLU_009161_3_1_1; -.
DR OMA; AMYKTYK; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000019118; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR048292; SDA1_C.
DR InterPro; IPR007949; SDA1_MD.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF21638; SDA1_C; 1.
DR Pfam; PF05285; SDA1_dom; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365057};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 61..423
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 492..626
FT /note="SDA1 middle"
FT /evidence="ECO:0000259|Pfam:PF05285"
FT DOMAIN 644..689
FT /note="SDA1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21638"
FT REGION 448..469
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 648..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..530
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..670
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ENN73106.1"
SQ SEQUENCE 690 AA; 79909 MW; 930156015BEE7DA0 CRC64;
MVRQNNQLAE NLPQLQNLIK RDPASYKEEF LAQRQQLTNI MSVFQLAPEQ SNKTINERVM
FMAQVAQCYP KEMEDFPQQI IDLMQKHNTV LNNNIRMGLC KALIMLRNKN LLAPTDLLEL
FFQLLKCQDK SLRQFLESHI ITDIKNMNVK HKNAKLNTTL QNFMFTMLKD SNSRAAKMSL
DIMIELYKKN IWNDAKTVNV IATGCFSKIT KIMVASLKFF LGKDPEEKDS DKSDSEEEVD
PKDVIMANKF NKKTRKRAKV LSKVKKLAAK SYKKKSQAVA FNFSAIHWLH DPQGMAEKLF
KQIEISNHRL EVKLMTLDVI SRLIGLHNLF LFNFYSYIQR FIQPHQREVT RILQFAAQAS
HELVPPDVIE PLLKTLANNF TTERNSSDVM AIGLNAVKEI CTRCPLSITE DLLRDLAGYK
SYKDRSVMMA AKGLIHLFRN LRPELLHKKD RGRPNEATDE MEKLDYGKTD AKDFVPGAEV
LLNEDHSEVS IELNSESESD DEQWVDVPHS DDGGSDEESD LDEEEEEDDT GRKILEPKRS
KAEILKEKKS LAQKVTIERL LTDEDFKRID LANVQKQMQS TKGSKRKLEE EALKNRDDLV
KLSDIENIYK KRKHDKQTRL ATVKEGQEGR EKFGYKDGRV NIHCSKTNRE KSKKKNAQMM
RHKAHGKVKR SFKDKQIALR NHLLKLKKMK
//
