ID N6UE82_DENPD Unreviewed; 969 AA.
AC N6UE82;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=116 kDa U5 small nuclear ribonucleoprotein component {ECO:0000256|ARBA:ARBA00018774};
DE AltName: Full=U5 snRNP-specific protein, 116 kDa {ECO:0000256|ARBA:ARBA00031432};
DE Flags: Fragment;
GN Name=109537783 {ECO:0000313|EnsemblMetazoa:ENN76962};
GN ORFNames=D910_01204 {ECO:0000313|EMBL:ERL83912.1}, D910_02314
GN {ECO:0000313|EMBL:ERL84891.1}, YQE_06530
GN {ECO:0000313|EMBL:ENN76962.1};
OS Dendroctonus ponderosae (Mountain pine beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Curculionidae; Scolytinae; Dendroctonus.
OX NCBI_TaxID=77166 {ECO:0000313|EMBL:ENN76962.1};
RN [1] {ECO:0000313|Proteomes:UP000019118, ECO:0000313|Proteomes:UP000030742}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M., Henderson H.,
RA Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A., W Huber D.P.,
RA Birol I., Jones S.J., Bohlmann J.;
RT "Draft genome of the mountain pine beetle, Dendroctonus ponderosae Hopkins,
RT a major forest pest.";
RL Genome Biol. 14:R27-R27(2013).
RN [2] {ECO:0000313|EnsemblMetazoa:ENN76962}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2017) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; APGK01038651; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KB740963; ENN76962.1; -; Genomic_DNA.
DR EMBL; KB630869; ERL83912.1; -; Genomic_DNA.
DR EMBL; KB631639; ERL84891.1; -; Genomic_DNA.
DR RefSeq; XP_019760230.1; XM_019904671.1.
DR AlphaFoldDB; N6UE82; -.
DR STRING; 77166.N6UE82; -.
DR EnsemblMetazoa; ENN76962; ENN76962; YQE_06530.
DR GeneID; 109537783; -.
DR KEGG; dpa:109537783; -.
DR HOGENOM; CLU_002794_11_2_1; -.
DR OMA; YIFRPIR; -.
DR OrthoDB; 166721at2759; -.
DR Proteomes; UP000019118; Unassembled WGS sequence.
DR Proteomes; UP000030742; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd04098; eEF2_C_snRNP; 1.
DR CDD; cd04090; EF2_II_snRNP; 1.
DR CDD; cd01683; EF2_IV_snRNP; 1.
DR CDD; cd16264; snRNP_III; 1.
DR CDD; cd04167; Snu114p; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031950; EFTUD2_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR044121; Snu114_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR InterPro; IPR035655; U5-116kDa_C.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF6; 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF16004; EFTUD2; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 122..400
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..44
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ENN76962.1"
SQ SEQUENCE 969 AA; 110321 MW; D1B84DAD6F49EA2F CRC64;
MDADLYDEFG NYVGPELDSD DEEEEEREQP DEDEQPEYDD ERMEDEPQPM AIVLHEDKQY
YPSSLQVYGP DVETIVQEED AQPLDVPLIE PVKKKKFQLK EQDLPETTYS MEFLADMMDN
TSLIRNVALV GHLHHGKTTF VDCLIRQTHP TYQDNEEKNL RYTDLLFTEQ ERGCSIKSVP
VTLLLQDIKN KSYLMNIFDT PGHVNFSDEV TAAMRLCDGI VLFIDAAEGV MLNTERLLKH
AVQEQMQITV CINKIDRLML ELKLPPQDAY YKLRHIVEEI NGLLTLYSDD ANPQIVSPVL
GNVCFASSQY GVCFTLKSFA NIYNLYHGDV NVDEFSKRLW GDIYFNPKNR KFTKKAPHNS
AQRSFVEFIL EPLYKVFAQV VGDVDSTLPK VLEELGIKLT KNEMKLNIRP LLRLVCNKFL
GDFNGFVNMC VEHIKSPLDN AKTKIDYIYT GPHSSKVYDD MIHCDQEGLL MVHSSKMYPT
EDCTFFQVLG RVMSGTLHAG TDLRILGENY TLQDEEDSRV LTIGRLWVYE SRYKVELNRV
PAGNWVLIEG IDQSIVKTAT ITDLSINDDL YIFRPLKFNT QSIIKIAVEP VNPSELPKML
DGLRKVNKSY PLLTTRVEES GEHVVLGTGE LYLDCVMHDL RKMYSEIDIK VADPVVAFCE
TVVETSSLKC FAETPNKKNK LTMIAEPLEK GLAEDIENES VQIGWNKKKL GEFFQTKYDW
DLLAARSIWA FGPDNTGPNI LVDDTLPSEV DKGLLSSVKD SIVQGFQWGT REGPLCEEPI
RNSKFKILDA VIAQEPLHRG GGQIIPTARR VVYSAFLMAT PRLMEPYLFV EVQAPADCVS
AVYTVLAKRR GHVTQDAPVP GSPLYTIKAF IPAIDSFGFE TDLRTHTQGQ AFCLSVFHHW
QIVPGDPLDK SIIIRPLEPQ PATHLAREFM IKTRRRKGLS QDVSINKFFD DPMLLELARQ
DVMLNYPLL
//
