ID N6VPX3_BARVB Unreviewed; 310 AA.
AC N6VPX3;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 03-MAY-2023, entry version 23.
DE SubName: Full=Cyclohexadienyl dehydrogenase {ECO:0000313|EMBL:ENN93087.1};
GN Name=tyrC {ECO:0000313|EMBL:ENN93087.1};
GN ORFNames=BVtw_17430 {ECO:0000313|EMBL:ENN93087.1};
OS Bartonella vinsonii subsp. berkhoffii str. Tweed.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Bartonellaceae; Bartonella.
OX NCBI_TaxID=1094502 {ECO:0000313|EMBL:ENN93087.1, ECO:0000313|Proteomes:UP000014011};
RN [1] {ECO:0000313|EMBL:ENN93087.1, ECO:0000313|Proteomes:UP000014011}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tweed {ECO:0000313|EMBL:ENN93087.1};
RX PubMed=23555299; DOI=10.1371/journal.pgen.1003393;
RA Guy L., Nystedt B., Toft C., Zaremba-Niedzwiedzka K., Berglund E.C.,
RA Granberg F., Naslund K., Eriksson A.S., Andersson S.G.;
RT "A gene transfer agent and a dynamic repertoire of secretion systems hold
RT the keys to the explosive radiation of the emerging pathogen Bartonella.";
RL PLoS Genet. 9:E1003393-E1003393(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENN93087.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AGWD01000027; ENN93087.1; -; Genomic_DNA.
DR RefSeq; WP_010705904.1; NZ_KB915638.1.
DR AlphaFoldDB; N6VPX3; -.
DR PATRIC; fig|1094502.3.peg.2178; -.
DR HOGENOM; CLU_055968_0_1_5; -.
DR Proteomes; UP000014011; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 7..296
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 310 AA; 33732 MW; 2AF316F3D3514DDF CRC64;
MLHIQFEKIA VIGIGLIGSS LARVIKKKNL AAQISIATRR QETLKRAREL ELGNFYTTDN
AEAVEGADLV IVSVPVGASA EVAKNIRDHL KPGAIVSDVG STKALVIAEM APLLPKSVHF
IPGHPIAGTE YSGPDAGFAD LFMNRWCILT PFAESDAAAV VKLTAFWEAC GARVEKMDAK
HHDLVLAIVS HLPHLIAYNT VGTASDLEKV TNSEVIAYSA SGFRDFTRLA SSDPVMWRDI
CLHNKDAILE MLSRFSEGLA SLEQAIRLGD GETLFNFFTR TRAVRRNIIE AGQEIDAPDF
GRHNVSKKGE
//
