ID N6XCM7_9RHOO Unreviewed; 625 AA.
AC N6XCM7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Phenol 2-monooxygenase {ECO:0000313|EMBL:ENO77170.1};
DE EC=1.14.13.7 {ECO:0000313|EMBL:ENO77170.1};
GN ORFNames=C664_12595 {ECO:0000313|EMBL:ENO77170.1};
OS Thauera sp. 63.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Thauera.
OX NCBI_TaxID=497321 {ECO:0000313|EMBL:ENO77170.1, ECO:0000313|Proteomes:UP000013007};
RN [1] {ECO:0000313|EMBL:ENO77170.1, ECO:0000313|Proteomes:UP000013007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=63 {ECO:0000313|EMBL:ENO77170.1,
RC ECO:0000313|Proteomes:UP000013007};
RA Liu B., Shapleigh J.P., Frostegard A.H.;
RT "Draft Genome Sequences of 6 Strains from Genus Thauera.";
RL Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the PheA/TfdB FAD monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007801}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENO77170.1}.
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DR EMBL; AMXC01000013; ENO77170.1; -; Genomic_DNA.
DR RefSeq; WP_004260774.1; NZ_AMXC01000013.1.
DR AlphaFoldDB; N6XCM7; -.
DR eggNOG; COG0654; Bacteria.
DR OrthoDB; 3443359at2; -.
DR Proteomes; UP000013007; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0018662; F:phenol 2-monooxygenase activity; IEA:UniProtKB-EC.
DR CDD; cd02979; PHOX_C; 1.
DR Gene3D; 3.40.30.20; -; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012941; Phe_hydrox_C_dim_dom.
DR InterPro; IPR038220; PHOX_C_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43004:SF6; FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR43004; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR Pfam; PF07976; Phe_hydrox_dim; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000313|EMBL:ENO77170.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ENO77170.1}.
FT DOMAIN 24..392
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT DOMAIN 430..590
FT /note="Phenol hydroxylase C-terminal dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07976"
SQ SEQUENCE 625 AA; 69274 MW; 6503C7BEC0F301C3 CRC64;
MQFYLNGYKP GDPTLQDAAL PETADVVIIG SGPAGALLAA QLSSFPGIRT RLVERRNGPL
ELGQADGVAC RTVETFQAFG LAEELVREGY WVNETVFWRP SPDDRNKIAR TGRVQDVEDG
LSEFPHLIVN QARLQQMLLD YMRKSPSRLE CDYGLEFDAL KVDAEGEYPV EVKLRDVNTG
IMKTIRAKYV VGCDGARSKV RESIGAKLHG DFANHAWGVV DMLAVTDFPD IRLKSAIQSA
DEGNILLIPR EGGYMVRLYV DLGEVDPNNR DAIRDITQEQ VIATAQRVLH PYTLDVRHVV
WFSVYQVGQR VTDRFDDVLP EHAGSRLPRV FIAGDACHTH SAKAGQGMNV SMQDTFNLGW
KLISVLEGRA RPELLRTYST ERHAIAQGLI DFDREWSKIM ASPPKDPAHP ERGGVDPAEL
QAYFVKSGRF TAGMATHYPP STVLTAPDTH QALATGFTIG TRFHSAPVVR LADAKPMQLG
HVARADAAWR IYAFADASGT RLRALMDFLA DSSDSPVRRF TPTGADPDSV IDVRAVFQQY
HRELKVDELP TMLLPPKGRF GLLDYEKAFA PDLKSGQDIF ELRGIDRAQG AIVVVRPDQY
VANVLPLDAH DALTAFFAAF LIDRH
//
