ID N8X984_9GAMM Unreviewed; 502 AA.
AC N8X984;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
GN ORFNames=F967_01781 {ECO:0000313|EMBL:ENV05674.1};
OS Acinetobacter sp. CIP 102637.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1144669 {ECO:0000313|EMBL:ENV05674.1, ECO:0000313|Proteomes:UP000023788};
RN [1] {ECO:0000313|EMBL:ENV05674.1, ECO:0000313|Proteomes:UP000023788}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIP 102637 {ECO:0000313|EMBL:ENV05674.1,
RC ECO:0000313|Proteomes:UP000023788};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cerqueira G., Feldgarden M., Courvalin P., Perichon B.,
RA Grillot-Courvalin C., Clermont D., Rocha E., Yoon E.-J., Nemec A.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Acinetobacter sp. CIP 102637.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENV05674.1}.
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DR EMBL; APPG01000036; ENV05674.1; -; Genomic_DNA.
DR RefSeq; WP_004799344.1; NZ_KB849435.1.
DR AlphaFoldDB; N8X984; -.
DR PATRIC; fig|1144669.3.peg.1767; -.
DR HOGENOM; CLU_009031_5_1_6; -.
DR Proteomes; UP000023788; Unassembled WGS sequence.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07206; Pat_TGL3-4-5_SDP1; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR021771; Triacylglycerol_lipase_N.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF10; TRIACYLGLYCEROL LIPASE 4-RELATED; 1.
DR Pfam; PF11815; DUF3336; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000023788}.
FT DOMAIN 157..344
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
SQ SEQUENCE 502 AA; 57907 MW; 6C4A507B401E2A02 CRC64;
MLNKVQEKKD TYQTYRIDML QEQLQHASSY EEWREIALKL DEESGREVWK YDNESPYFDA
EVLSRRYNLL KRYRLHHRTL DLIYILRDGL TYDFANIGHP MLFAETYIGT KKIIENYVDE
VSDCLRYLAS SECITFQLKE KIKFFEECQK AYGQPALMLS GGATLGLFHT GVCKALLEQD
LLPKVLSGSS AGAIMTGMLG TSSADQIPEL LTGKHFFHEA FRFRKVMELI KGHGGIADVM
YLKKFLIHNM GDLTFAEAYQ RSGLHINIAV APYNASQNPL ILNALTAPNA LVWSAVMASC
AVPVLFPPVH LTSKRYDGQH TPYMSNTKWV DGSMRSDFPQ EKMARLYNIN YTIASQVNPH
IVPFMQSDLQ RYRNDVLSWP ERIIRHQGKT IALDVMDLTR HYVGRFFPIR RALDHGYGIL
GQRYYGDVNI IAKYGLRHYG YMLKNPRPKL FKILQQEGER ATWPKIASIE THARIGKTIE
HCLASLRKQA EKQQNEFYYV DL
//
