ID N8Y7K4_ACIGI Unreviewed; 501 AA.
AC N8Y7K4;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=HTH gntR-type domain-containing protein {ECO:0000259|PROSITE:PS50949};
GN ORFNames=F964_04339 {ECO:0000313|EMBL:ENV15613.1};
OS Acinetobacter guillouiae NIPH 991.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1217656 {ECO:0000313|EMBL:ENV15613.1, ECO:0000313|Proteomes:UP000013148};
RN [1] {ECO:0000313|EMBL:ENV15613.1, ECO:0000313|Proteomes:UP000013148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIPH 991 {ECO:0000313|EMBL:ENV15613.1,
RC ECO:0000313|Proteomes:UP000013148};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cerqueira G., Feldgarden M., Courvalin P., Perichon B.,
RA Grillot-Courvalin C., Clermont D., Rocha E., Yoon E.-J., Nemec A.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Acinetobacter guillouiae NIPH 991.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENV15613.1}.
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DR EMBL; APPJ01000014; ENV15613.1; -; Genomic_DNA.
DR RefSeq; WP_004823419.1; NZ_KB849456.1.
DR AlphaFoldDB; N8Y7K4; -.
DR PATRIC; fig|1217656.3.peg.4281; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_1_6; -.
DR Proteomes; UP000013148; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000013148};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 19..87
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 501 AA; 56797 MW; 2FBA97DA0C6136B1 CRC64;
MRSLLGDYLL QRLQQDIDGT LQLRLFRCLR NAIIDGVLAP KTRLPASRDL AKEIKVSRNT
VLSAYEQLQA QGYVNARTGQ GTWVADELPE SFLVKAENPH QPIQEKKSQQ SYSLSQRGSY
LIGYSAASPY QWGAFVPGEP DVTEFPHHIF SRIQTRLSRE PEINQLIYSN AGGSLELRQE
LAEYLKIARS VQCDADQIII TEGTHQAIDL VSRTLTDIGD EVWIEDPAYW GARNILRING
VNLRSLPVDQ DGIIPDLHPQ CPPKLIFVTP SHQYPLGSHL SLERRKQLIA FARQHQCWIV
EDDYDSEFRF SGQPYPSLQG LEPDSPVIYM GTFSKTIYPA LRIGYLVVPK KLFSPLRIVS
AELYRGGHLI DQKVLAEFIR EGHYGAHIRR MRLLYSKRHA FLIDLIYRHL GQDFLHEYNT
AAGLHLILKL PSHSDDVLIA SNALDQGVKV RALSQYYTKQ YSTQQKGLLL GFACVNEQAI
FVAFGILLKC LRDVGIPTLN H
//
