ID N9MJT9_9GAMM Unreviewed; 421 AA.
AC N9MJT9;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=F905_00197 {ECO:0000313|EMBL:ENW90189.1};
OS Acinetobacter sp. CIP 53.82.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1144671 {ECO:0000313|EMBL:ENW90189.1, ECO:0000313|Proteomes:UP000018455};
RN [1] {ECO:0000313|EMBL:ENW90189.1, ECO:0000313|Proteomes:UP000018455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIP 53.82 {ECO:0000313|EMBL:ENW90189.1,
RC ECO:0000313|Proteomes:UP000018455};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cerqueira G., Feldgarden M., Courvalin P., Perichon B.,
RA Grillot-Courvalin C., Clermont D., Rocha E., Yoon E.-J., Nemec A.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Acinetobacter sp. CIP 53.82.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENW90189.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; APRK01000008; ENW90189.1; -; Genomic_DNA.
DR RefSeq; WP_005176086.1; NZ_KB850045.1.
DR AlphaFoldDB; N9MJT9; -.
DR GeneID; 69465212; -.
DR PATRIC; fig|1144671.3.peg.182; -.
DR HOGENOM; CLU_018816_2_1_6; -.
DR Proteomes; UP000018455; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..421
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004148145"
FT DOMAIN 54..366
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 70..298
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 381..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 421 AA; 44844 MW; 488053431939326D CRC64;
MMSAKLWAPA LTACALATSI ALVGCSKDPN DAQQAAAQQQ MPPTEVGVIV VQPQSVEQSV
ELSGRTTAFE ISEVRPQTSG VVQKRLFTEG SYVREGQALY EIDSRTNRAS VDSARAALAR
QQANLNVLRV KEGRYRQLVG SNAISKQEYD DIVAQVKLAE ADVAATRAEL RNAEINLGYS
TVRAPISGQT NRSTVTAGAL VTASQQEPLV TIQRLDPIYV DINQSSAELL RLRQQLSKGD
LNSSNNTTVK LKLEDGSYYP VEGRLAFSDA SVNPDTGTVT LRAVFPNPNH LLLPGMFATA
QIVQGVIPNA VLIPQAAITR TPTGQAMAML VNAKGVVEPR PVTTAGIQGK DWIVTEGLQT
GDKVIVEGIA KVKPEQKVVA KPYQPQAAAP QGAQQPAASD KAKQPADQAD AQAEQKATSN
T
//
