GenomeNet

Database: UniProt
Entry: N9U0A1_9MOLU
LinkDB: N9U0A1_9MOLU
Original site: N9U0A1_9MOLU 
ID   N9U0A1_9MOLU            Unreviewed;       457 AA.
AC   N9U0A1;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   05-JUL-2017, entry version 29.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000313|EMBL:ENY53987.1};
GN   ORFNames=MALK_3350 {ECO:0000313|EMBL:ENY53987.1};
OS   Mycoplasma alkalescens 14918.
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=1188234 {ECO:0000313|EMBL:ENY53987.1, ECO:0000313|Proteomes:UP000013137};
RN   [1] {ECO:0000313|EMBL:ENY53987.1, ECO:0000313|Proteomes:UP000013137}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=14918 {ECO:0000313|EMBL:ENY53987.1,
RC   ECO:0000313|Proteomes:UP000013137};
RX   PubMed=23766408;
RA   Manso-Silvan L., Tardy F., Baranowski E., Barre A., Blanchard A.,
RA   Breton M., Couture C., Citti C., Dordet-Frisoni E., Dupuy V.,
RA   Gaurivaud P., Jacob D., Lemaitre C., Nikolski M., Nouvel L.X.,
RA   Poumarat F., Thebault P., Theil S., Thiaucourt F., Sirand-Pugnet P.;
RT   "Draft Genome Sequences of Mycoplasma alkalescens, Mycoplasma
RT   arginini, and Mycoplasma bovigenitalium, Three Species with Equivocal
RT   Pathogenic Status for Cattle.";
RL   Genome Announc. 1:e00348-13(2013).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|RuleBase:RU000577,
CC       ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ENY53987.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AMWK01000006; ENY53987.1; -; Genomic_DNA.
DR   RefSeq; WP_002881396.1; NZ_AMWK01000006.1.
DR   EnsemblBacteria; ENY53987; ENY53987; MALK_3350.
DR   PATRIC; fig|1188234.3.peg.308; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000013137; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000013137};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000577,
KW   ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013137}.
FT   DOMAIN      148    283       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      363    432       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   457 AA;  52978 MW;  2C88F7872AC1655D CRC64;
     MNYKDEELDL NISNQILQNE LKNTASDSMT YESFFSQLKL IFVSNDNAYI LVPTYIIDYI
     KTTFYETIQR ALINALEKKV SLTFISDIDE IKELVNKEKT TKFIKNETQN KSNNNVKNNL
     TFENYAIGNF NKMALKAAKE ISKEYKDNYN PLFIYSSSGL GKTHLLHAIG NEFVKKNKTC
     LYVNPDILTR RLVEQLRLKN QEQINKIVDE LTSYDCLMFD DVQQYGNKES TLNVLFNVIN
     IMKSNHKQII FCADKSPNQL GGFEQRFLTR FEGGLTIEIN NLELEDVISV LKFKLKENHI
     NVDLWEDAAL RYIARNFSTS IRSIEGAISR IKLFSDGDDF FTYDLHTMQN IFKNVTKSKE
     SITPERIIET VCKYYGVDRK KIISSSRVKE IVIPRKIIIY FLKNNFDFTL KEIGKMVGDQ
     THSTVIASLK WIEANIQSNS SLKNAIEKIQ NMLKKII
//
DBGET integrated database retrieval system