ID N9UNB7_9SPHN Unreviewed; 572 AA.
AC N9UNB7;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=EBMC1_17022 {ECO:0000313|EMBL:ENY79834.1};
OS Sphingopyxis sp. MC1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=1174684 {ECO:0000313|EMBL:ENY79834.1, ECO:0000313|Proteomes:UP000013072};
RN [1] {ECO:0000313|EMBL:ENY79834.1, ECO:0000313|Proteomes:UP000013072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MC1 {ECO:0000313|EMBL:ENY79834.1,
RC ECO:0000313|Proteomes:UP000013072};
RA Lolas I.B., Kjeldal H., Almeida B., Le-Quy V., Gough H.L., Nielsen J.L.;
RT "Differential expression analysis of membrane associated proteins from
RT triclosan-degrading sphingopyxis.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENY79834.1}.
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DR EMBL; AOUN01000024; ENY79834.1; -; Genomic_DNA.
DR RefSeq; WP_003052584.1; NZ_AOUN01000024.1.
DR AlphaFoldDB; N9UNB7; -.
DR PATRIC; fig|1174684.3.peg.3435; -.
DR eggNOG; COG1793; Bacteria.
DR Proteomes; UP000013072; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ENY79834.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013072}.
FT DOMAIN 348..478
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 572 AA; 62979 MW; 624733483222D70F CRC64;
MKRFAALIDR LIYTRSRNSK LALIVDYLKH TPDPDRGWAL AALTEALDFP AVKAGTVRTL
LATRLDEELF RLSRHFVGDT AETAALLWPD SDNRTETIRI PERSRGALSS AARISGVAAS
TSLGMAPRLR SGMRDSDTAQ SSLSVSEAVD ALAAASRSDA PAIVAALLDR LDADGRYALL
KLALGGMRVG VSARLAKQAF AQAFGVPVDD VEELWHAIPP PYAPLFAWGE GRAPRPDLAD
VAFFRPFMLA HPLEQEAIDL ADFAAEWKWD GIRVQIVRAA GETRIYSRGG EEISGAFPEL
VAAFDQEAVI DGELLVRGEV QGGPETQGGA ASFNALQQRL GRKTVSKKML ADYPAFVRVY
DLLAVAGDDL RGLPWTERRR QLEAFVPRLA ASHFDLSPLI AAEDFSALAD LRAGARDAAI
EGVMLKRRDA PYVAGRRAGL WYKWKRDPLT ADCVMMYAQR GNGRRASFYS DYTFGCWTEA
GELLPVGKAY SGFTDAELKW LDKFVRDNTV DRFGPVREVE KTLVLEVAFD SIHASKRHKS
GLAMRFPRIA RIRRDKPAEE ADRIATLRSM VT
//
