ID N9WDF0_9CLOT Unreviewed; 447 AA.
AC N9WDF0;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=TldD/PmbA family protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF1092_02230 {ECO:0000313|EMBL:ENZ01061.1};
OS Clostridium thermobutyricum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=29372 {ECO:0000313|EMBL:ENZ01061.1, ECO:0000313|Proteomes:UP000013097};
RN [1] {ECO:0000313|EMBL:ENZ01061.1, ECO:0000313|Proteomes:UP000013097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=209318 {ECO:0000313|EMBL:ENZ01061.1,
RC ECO:0000313|Proteomes:UP000013097};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Courvalin P., Lambert T.,
RA Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium colicanis 209318.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ENZ01061.1}.
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DR EMBL; AGYT01000010; ENZ01061.1; -; Genomic_DNA.
DR RefSeq; WP_002598718.1; NZ_KB850956.1.
DR AlphaFoldDB; N9WDF0; -.
DR PATRIC; fig|999411.4.peg.2193; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_026425_4_0_9; -.
DR Proteomes; UP000013097; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR047657; PmbA.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000013097}.
FT DOMAIN 23..86
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 114..216
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 225..446
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 447 AA; 49503 MW; 45CF5A03E46B0F0E CRC64;
MEFKEFKEKL FNKSREEGLE EFEIYFSDKE SLSINIYKEE VEKYSLNKSF GVSFRAKINE
KMGYSYTEII DEASIDMLIN NAKAAALYIE DDDKQFIYEG DKEYSKVENY HPQLENIEAD
KLIELGIQME KECKKESDKI ANFGGCGIGY VNVKYGLMNS KGLELTDKSN LLTAYIVPIL
DIDDVKYDGF GYSVAKSIED VNPNKIAKMA IKEAMDKVGA KTIESKKYKT VIKNEAMVSL
LQSFWSIFDG DLAQKGISLL GGKEGEIIAS DKLTIIDNPL MKDGLASVAF DDEGVATFKK
SIIENGKLVT LLHNLKTANK VNRKSTGSGF KNSYASPVSV GPTNFYIEEG ATTFEQLLEE
VKDGLIVTEF SGLHSGANSI TGDFSLAAKG FLIVDGKQGR PVEQITVAGN FFELLKNIQV
VCSDIKFPMT SFGSPSIYVG EMSVAGE
//
