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Database: UniProt
Entry: NAS3_HORVU
LinkDB: NAS3_HORVU
Original site: NAS3_HORVU 
ID   NAS3_HORVU              Reviewed;         335 AA.
AC   Q9ZQV8;
DT   13-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   01-OCT-2014, entry version 43.
DE   RecName: Full=Probable nicotianamine synthase 3;
DE            EC=2.5.1.43;
DE   AltName: Full=HvNAS3;
DE   AltName: Full=S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-methionine 3-amino-3-carboxypropyltransferase 3;
GN   Name=NAS3;
OS   Hordeum vulgare (Barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade;
OC   Pooideae; Triticeae; Hordeum.
OX   NCBI_TaxID=4513;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Ehimehadaka No.1; TISSUE=Root;
RX   PubMed=9952442; DOI=10.1104/pp.119.2.471;
RA   Higuchi K., Suzuki K., Nakanishi H., Yamaguchi H., Nishizawa N.-K.,
RA   Mori S.;
RT   "Cloning of nicotianamine synthase genes, novel genes involved in the
RT   biosynthesis of phytosiderophores.";
RL   Plant Physiol. 119:471-480(1999).
CC   -!- FUNCTION: Synthesizes nicotianamine, a polyamine that is the first
CC       intermediate in the synthesis of the phytosiderophores of the
CC       mugineic acid type found in gramineae which serves as a sensor for
CC       the physiological iron status within the plant, and/or might be
CC       involved in the transport of iron. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY: 3 S-adenosyl-L-methionine = 3 S-methyl-5'-
CC       thioadenosine + nicotianamine.
CC   -!- SIMILARITY: Belongs to the nicotianamine synthase (NAS)-like
CC       family. {ECO:0000305}.
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DR   EMBL; AB011264; BAA74581.1; -; mRNA.
DR   ProteinModelPortal; Q9ZQV8; -.
DR   Gramene; Q9ZQV8; -.
DR   Genevestigator; Q9ZQV8; -.
DR   GO; GO:0030410; F:nicotianamine synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030418; P:nicotianamine biosynthetic process; IEA:InterPro.
DR   GO; GO:0010233; P:phloem transport; IEA:EnsemblPlants/Gramene.
DR   GO; GO:0009555; P:pollen development; IEA:EnsemblPlants/Gramene.
DR   GO; GO:0009860; P:pollen tube growth; IEA:EnsemblPlants/Gramene.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR004298; Nicotian_synth.
DR   InterPro; IPR029063; SAM-dependent_MTases-like.
DR   Pfam; PF03059; NAS; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS51142; NAS; 1.
PE   2: Evidence at transcript level;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    335       Probable nicotianamine synthase 3.
FT                                /FTId=PRO_0000212706.
SQ   SEQUENCE   335 AA;  36015 MW;  956687E49A55215F CRC64;
     MAAQNNNKDV AALVEKITGL HAAIAKLPSL SPSPDVDALF TELVTACVPP SPVDVTKLGP
     EAQEMREGLI RLCSEAEGKL EAHYSDMLAA FDNPLDHLGI FPYYSNYINL SKLEYELLAR
     YVRRHRPARV AFIGSGPLPF SSFVLAARHL PDTMFDNYDL CGAANDRASK LFRADTDVGA
     RMSFHTADVA DLASELAKYD VVFLAALVGM AAEDKAKVIA HLGAHMADGA ALVVRSAHGA
     RGFLYPIVDP QDIGRGGFEV LAVCHPDDDV VNSVIIAQKS KEVHADGLGS ARGAGRQYAR
     GTVPVVSPPC RFGEMVADVT QNHKRDEFAN AEVAF
//
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