ID NCBP1_ORYSJ Reviewed; 867 AA.
AC Q10LJ0; A0A0N7KH92; B9F8F3; Q9AWB3;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 22-AUG-2006, sequence version 1.
DT 24-JAN-2024, entry version 106.
DE RecName: Full=Nuclear cap-binding protein subunit 1;
DE AltName: Full=80 kDa nuclear cap-binding protein;
DE Short=CBP80;
DE Short=NCBP 80 kDa subunit;
GN Name=ABH1; Synonyms=CBP80; OrderedLocusNames=Os03g0347200, LOC_Os03g22570;
GN ORFNames=OsJ_10823;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Nipponbare;
RA Derba M., Kmieciak M., Jarmolowski A.;
RT "Molecular characterization of Oryza sativa CBP80.";
RL Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Component of the cap-binding complex (CBC), which binds
CC cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in
CC various processes such as pre-mRNA splicing and RNA-mediated gene
CC silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in
CC miRNA-mediated RNA interference and is required for primary miRNA
CC processing. In the CBC complex, ABH1/CBP80 does not bind directly
CC capped RNAs (m7GpppG-capped RNA) but is required to stabilize the
CC movement of the N-terminal loop of CBP20 and lock the CBC into a high
CC affinity cap-binding state with the cap structure (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the nuclear cap-binding complex (CBC), a
CC heterodimer composed of ABH1/CBP80 and CBP20 that interacts with
CC m7GpppG-capped RNA.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC Note=Predominantly nuclear. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NCBP1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG54079.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=AK102852; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=EEE59051.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY017415; AAG54079.1; ALT_FRAME; mRNA.
DR EMBL; DP000009; ABF95910.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF12011.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS84169.1; -; Genomic_DNA.
DR EMBL; CM000140; EEE59051.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AK102852; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q10LJ0; -.
DR SMR; Q10LJ0; -.
DR STRING; 39947.Q10LJ0; -.
DR PaxDb; 39947-Q10LJ0; -.
DR EnsemblPlants; Os03t0347200-01; Os03t0347200-01; Os03g0347200.
DR Gramene; Os03t0347200-01; Os03t0347200-01; Os03g0347200.
DR eggNOG; KOG1104; Eukaryota.
DR HOGENOM; CLU_013207_1_0_1; -.
DR InParanoid; Q10LJ0; -.
DR OMA; CAAEGLM; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR ExpressionAtlas; Q10LJ0; baseline and differential.
DR Genevisible; Q10LJ0; OS.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005845; C:mRNA cap binding complex; IBA:GO_Central.
DR GO; GO:0005846; C:nuclear cap binding complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0000339; F:RNA cap binding; IBA:GO_Central.
DR GO; GO:0006370; P:7-methylguanosine mRNA capping; IEA:UniProtKB-KW.
DR GO; GO:1901527; P:abscisic acid-activated signaling pathway involved in stomatal movement; IEA:EnsemblPlants.
DR GO; GO:0000380; P:alternative mRNA splicing, via spliceosome; IEA:EnsemblPlants.
DR GO; GO:0051607; P:defense response to virus; IEA:EnsemblPlants.
DR GO; GO:0048574; P:long-day photoperiodism, flowering; IEA:EnsemblPlants.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IBA:GO_Central.
DR GO; GO:0031053; P:primary miRNA processing; IEA:EnsemblPlants.
DR GO; GO:0000394; P:RNA splicing, via endonucleolytic cleavage and ligation; IEA:EnsemblPlants.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027159; CBP80.
DR InterPro; IPR015172; MIF4G-like_typ-1.
DR InterPro; IPR015174; MIF4G-like_typ-2.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR12412; CAP BINDING PROTEIN; 1.
DR PANTHER; PTHR12412:SF2; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1; 1.
DR Pfam; PF02854; MIF4G; 1.
DR Pfam; PF09088; MIF4G_like; 1.
DR Pfam; PF09090; MIF4G_like_2; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
PE 2: Evidence at transcript level;
KW Cytoplasm; mRNA capping; mRNA processing; mRNA splicing; Nucleus;
KW Reference proteome; RNA-mediated gene silencing.
FT CHAIN 1..867
FT /note="Nuclear cap-binding protein subunit 1"
FT /id="PRO_0000385247"
FT DOMAIN 9..228
FT /note="MIF4G"
FT REGION 752..797
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 763..797
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 23
FT /note="A -> V (in Ref. 1; AAG54079)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 867 AA; 98890 MW; 251B2B3A180EBB39 CRC64;
MSAGWRTLLL RIGDRCPEYG GSADHKEHIE TCYGVLCREY EHSKDAMFEF LLQCADQLPH
KIPFFGVLIG LINLENEDFS KGIVDTTHAN LQDALHNENR DRIRILLRFL CGLMCSKVVL
PNSIIETFEA LLSSAATILD EETGNPSWQP RADFYVYCIL ASLPWGGSEL FEQVPDEFER
VLVGIQSYIS IRRHFDDIAF SVFETDEGNS PNKKDFIEDL WERIQVLSRN GWKVKSVPKP
HLSFEAQLVA GVSHRFSPIS CPPPTISQSS SEIVKGQEKH EADLKYPQRL RRLHIFPTNK
AENMQPVDRF VVEECILDVL LFFNGCRKEC AFYLVSLPVP FRYEYLMAET IFSQLLLLPN
PPFRPIYYTL VIIDLCKALP GAFPSVVVGA VHALFDRISN MDMECRTRLI LWFSHHLSNF
QFIWPWQEWA YVKDLPKWAP QRVFVQEVLE REIRLSYFDK IKQSIEDAVE LEELLPPKAG
PNFRYHSDEG KESTDGHRLS KELVAMVRGR KTQGDIISWV DEKIIPVNGA KFALDVVSQT
LLDIGSKSFT HLITVLERYG QIISKLCPNE EMQLLLMDEV SAYWKNSTQM IAIAIDRMMG
YRLLSNLAIV KWVFSPANVD QFHVSDRPWE ILRNAVSKTY NRIFDLRKEI QTLRKGLQAA
KEASEKAARE LEEAKSIIEI VDGQPVPSEN PGRLRRLQAR ADKAKEGEVT TEESLEAKEA
LLARGLEESK ELLRLLFKSF VEVLTERLPP ISADGDVPNL RAGDPNVNSS ARDPEATTME
IDNENGGDND SQLNGQNKKI SHNVGELEQW CLCTLGYLKS FSRQYATEIW SHIAMLDQEI
FVGNIHPLIR KAAFSGLCRP TSEGSHL
//
