ID NRDR2_MAGSA Reviewed; 153 AA.
AC Q2W5J7;
DT 05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 10-JAN-2006, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=Transcriptional repressor NrdR 2 {ECO:0000255|HAMAP-Rule:MF_00440};
GN Name=nrdR2 {ECO:0000255|HAMAP-Rule:MF_00440}; OrderedLocusNames=amb2074;
OS Magnetospirillum magneticum (strain AMB-1 / ATCC 700264).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Magnetospirillaceae; Paramagnetospirillum.
OX NCBI_TaxID=342108;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AMB-1 / ATCC 700264;
RX PubMed=16303747; DOI=10.1093/dnares/dsi002;
RA Matsunaga T., Okamura Y., Fukuda Y., Wahyudi A.T., Murase Y., Takeyama H.;
RT "Complete genome sequence of the facultative anaerobic magnetotactic
RT bacterium Magnetospirillum sp. strain AMB-1.";
RL DNA Res. 12:157-166(2005).
CC -!- FUNCTION: Negatively regulates transcription of bacterial
CC ribonucleotide reductase nrd genes and operons by binding to NrdR-
CC boxes. {ECO:0000255|HAMAP-Rule:MF_00440}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00440};
CC Note=Binds 1 zinc ion. {ECO:0000255|HAMAP-Rule:MF_00440};
CC -!- SIMILARITY: Belongs to the NrdR family. {ECO:0000255|HAMAP-
CC Rule:MF_00440}.
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DR EMBL; AP007255; BAE50878.1; -; Genomic_DNA.
DR RefSeq; WP_011384474.1; NC_007626.1.
DR AlphaFoldDB; Q2W5J7; -.
DR SMR; Q2W5J7; -.
DR STRING; 342108.amb2074; -.
DR KEGG; mag:amb2074; -.
DR HOGENOM; CLU_108412_0_1_5; -.
DR OrthoDB; 9807461at2; -.
DR Proteomes; UP000007058; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00440; NrdR; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR003796; RNR_NrdR-like.
DR NCBIfam; TIGR00244; transcriptional regulator NrdR; 1.
DR PANTHER; PTHR30455; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR PANTHER; PTHR30455:SF2; TRANSCRIPTIONAL REPRESSOR NRDR; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA-binding; Metal-binding; Nucleotide-binding;
KW Reference proteome; Repressor; Transcription; Transcription regulation;
KW Zinc; Zinc-finger.
FT CHAIN 1..153
FT /note="Transcriptional repressor NrdR 2"
FT /id="PRO_0000249025"
FT DOMAIN 49..139
FT /note="ATP-cone"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00440"
FT ZN_FING 3..34
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00440"
SQ SEQUENCE 153 AA; 17505 MW; 947FA825341F307A CRC64;
MRCPFCGQDD TQVKDSRPTD DNAAIRRRRA CPGCGSRFTT FERVQIRDLV VVKKDGSRST
FDREKVVKSL QIALRKRPVE DDQIERIANG IYRRLESLGE NEVPSKLIGE LVMDVLMEMD
QVAYLRYASV YRNFREAKDF GDFLGKMGTS SGD
//
