ID NTPTH_PYRKO Reviewed; 180 AA.
AC Q5JF42;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 01-MAY-2013, entry version 59.
DE RecName: Full=Nucleoside-triphosphatase THEP1;
DE Short=NTPase THEP1;
DE EC=3.6.1.15;
DE AltName: Full=Nucleoside triphosphate phosphohydrolase;
GN OrderedLocusNames=TK0557;
OS Pyrococcus kodakaraensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OS (Thermococcus kodakaraensis (strain KOD1)).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=69014;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-918 / JCM 12380 / KOD1;
RX PubMed=15710748; DOI=10.1101/gr.3003105;
RA Fukui T., Atomi H., Kanai T., Matsumi R., Fujiwara S., Imanaka T.;
RT "Complete genome sequence of the hyperthermophilic archaeon
RT Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus
RT genomes.";
RL Genome Res. 15:352-363(2005).
CC -!- FUNCTION: Has nucleotide phosphatase activity towards ATP, GTP,
CC CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower
CC efficiency (By similarity).
CC -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate.
CC -!- SIMILARITY: Belongs to the THEP1 NTPase family.
CC -----------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution-NoDerivs License
CC -----------------------------------------------------------------------
DR EMBL; AP006878; BAD84746.1; -; Genomic_DNA.
DR RefSeq; YP_182970.1; NC_006624.1.
DR ProteinModelPortal; Q5JF42; -.
DR STRING; 69014.TK0557; -.
DR EnsemblBacteria; BAD84746; BAD84746; TK0557.
DR GeneID; 3233781; -.
DR KEGG; tko:TK0557; -.
DR eggNOG; COG1618; -.
DR HOGENOM; HOG000006446; -.
DR KO; K06928; -.
DR OMA; VTKENRN; -.
DR ProtClustDB; PRK13695; -.
DR GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:HAMAP.
DR GO; GO:0019204; F:nucleotide phosphatase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:InterPro.
DR HAMAP; MF_00796; NTPase_1; 1; -.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR004948; Nuc-triphosphatase_THEP1.
DR Pfam; PF03266; NTPase_1; 1.
DR SMART; SM00382; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding; Complete proteome; Hydrolase; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1 180 Nucleoside-triphosphatase THEP1.
FT /FTId=PRO_0000146704.
FT NP_BIND 9 16 ATP (By similarity).
FT NP_BIND 104 111 ATP (By similarity).
SQ SEQUENCE 180 AA; 20001 MW; 40F7B3D6BEFF019A CRC64;
MALRIFVTGP AGVGKTTLVE RVAREVDRWG YIVGGVITRE VRRGGRRIGF KITALDTGEE
GTLASLRGTS HLPGVPFGKY VVHVDEIERV AVPAIRRAIV EADLIVIDEI GPMEYTSNEF
IRAVGEVLKS EKPLLAVVHR KFIDRFRPLG EVHTLSFENR NAEFGIILDR VMKELKGIRG
//
