ID NUSB_COREF Reviewed; 188 AA.
AC Q8FT35;
DT 20-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073}; OrderedLocusNames=CE1736;
OS Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189
OS / NBRC 100395).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=196164;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395;
RX PubMed=12840036; DOI=10.1101/gr.1285603;
RA Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E., Sugimoto S.,
RA Matsui K., Yamagishi A., Kikuchi H., Ikeo K., Gojobori T.;
RT "Comparative complete genome sequence analysis of the amino acid
RT replacements responsible for the thermostability of Corynebacterium
RT efficiens.";
RL Genome Res. 13:1572-1579(2003).
CC -!- FUNCTION: Involved in transcription antitermination. Required for
CC transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC {ECO:0000255|HAMAP-Rule:MF_00073}.
CC -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC Rule:MF_00073}.
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DR EMBL; BA000035; BAC18546.1; -; Genomic_DNA.
DR RefSeq; WP_011075582.1; NZ_GG700683.1.
DR AlphaFoldDB; Q8FT35; -.
DR SMR; Q8FT35; -.
DR STRING; 196164.gene:10742157; -.
DR KEGG; cef:CE1736; -.
DR eggNOG; COG0781; Bacteria.
DR HOGENOM; CLU_087843_2_0_11; -.
DR OrthoDB; 3528057at2; -.
DR Proteomes; UP000001409; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.940.10; NusB-like; 1.
DR HAMAP; MF_00073; NusB; 1.
DR InterPro; IPR035926; NusB-like_sf.
DR InterPro; IPR011605; NusB_fam.
DR InterPro; IPR006027; NusB_RsmB_TIM44.
DR NCBIfam; TIGR01951; nusB; 1.
DR PANTHER; PTHR11078:SF3; ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11078; N UTILIZATION SUBSTANCE PROTEIN B-RELATED; 1.
DR Pfam; PF01029; NusB; 1.
DR SUPFAM; SSF48013; NusB-like; 1.
PE 3: Inferred from homology;
KW Reference proteome; RNA-binding; Transcription;
KW Transcription antitermination; Transcription regulation.
FT CHAIN 1..188
FT /note="Transcription antitermination protein NusB"
FT /id="PRO_0000176532"
FT REGION 154..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 188 AA; 20611 MW; C5C816631C6280E9 CRC64;
MSESRQGYKR HGARYKARRR AVDILFEAES RDVDPVAIID DRKTLSNAVD PVVAPVAEYT
EAIINGVAVE LDTIDDLLSE HIADTWLLER LPSVDRAVLR VACWEMLYNP DVPVTTAVVE
AVEIASQYST DKAGAYINAT LDNMASKVDE LRERAANPGA VSGSDAPVAP WDDSEELPAE
DEAEDSRP
//
