ID   O00184_HUMAN            Unreviewed;       579 AA.
AC   O00184;
DT   01-JUL-1997, integrated into UniProtKB/TrEMBL.
DT   01-JUL-1997, sequence version 1.
DT   24-JAN-2024, entry version 89.
DE   RecName: Full=Syntaxin-binding protein 2 {ECO:0000256|ARBA:ARBA00040518};
DE   AltName: Full=Protein unc-18 homolog 2 {ECO:0000256|ARBA:ARBA00042595};
DE   AltName: Full=Protein unc-18 homolog B {ECO:0000256|ARBA:ARBA00042592};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAA19547.1};
RN   [1] {ECO:0000313|EMBL:BAA19547.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Lymphoid {ECO:0000313|EMBL:BAA19547.1};
RA   Abe Y., Takaoka Y.;
RT   "hunc18b2 from LAK subtraction library.";
RL   Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC       {ECO:0000256|ARBA:ARBA00009884}.
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DR   EMBL; AB002559; BAA19547.1; -; mRNA.
DR   AlphaFoldDB; O00184; -.
DR   PeptideAtlas; O00184; -.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.40.60; -; 1.
DR   Gene3D; 3.40.50.1910; -; 1.
DR   Gene3D; 3.40.50.2060; -; 1.
DR   InterPro; IPR043154; Sec-1-like_dom1.
DR   InterPro; IPR043127; Sec-1-like_dom3a.
DR   InterPro; IPR001619; Sec1-like.
DR   InterPro; IPR027482; Sec1-like_dom2.
DR   InterPro; IPR036045; Sec1-like_sf.
DR   PANTHER; PTHR11679:SF27; SYNTAXIN-BINDING PROTEIN 2; 1.
DR   PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR   Pfam; PF00995; Sec1; 1.
DR   PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR   SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE   2: Evidence at transcript level;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Transport {ECO:0000256|ARBA:ARBA00022927}.
FT   REGION          444..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          559..579
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        563..579
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   579 AA;  64691 MW;  C9507EFF8CA369AE CRC64;
     MAPSGLKAVV GEKILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI LAEGITIVED
     INKRREPIPS LEAIYLLSPT EKSVQALIKD FQGTPTFTYK AAHIFFTDTC PEPLFSELGR
     SRLAKVVKTL KEIHLAFLPY EAQVFSLDAP HSTYNLYCPF RAEERTRQLE VLAQQIATLC
     ATLQEYPAIR YRKGPEDTAQ LAHAVLAKLN AFKADTPSLG EGPEKTRSQL LIMDRAADPV
     SPLLHELTFQ AMAYDLLDIE QDTYRYETTG LSEAREKAVL LDEDDDLWVE LRHMHIADVS
     KKVTELLRTF CESKRLTTDK ANIKDLSQIL KKMPQYQKEL NKYSTHLHLA DDCMKHFKGS
     VEKLCSVEQD LAMGSDAEGE KIKDSMKLIV PVLLDAAVPA YDKIRVLLLY ILLRNGVSEE
     NLAKLIQHAN VQAHSSLIRN LEQLGGTVTN PGGSGTSSRL EPRERMEPTY QLSRWTPVIK
     DVMEDAVEDR LDRNLWPFVS DPAPTASSQA AVSARFGHWH KNKAGVEARA GPRLIVYVMG
     GVAMSEMRAA YEVTRATEGS GRCSLAPHTS SPRPASWMT
//