ID O05326_PSESP Unreviewed; 200 AA.
AC O05326;
DT 01-JUL-1997, integrated into UniProtKB/TrEMBL.
DT 01-JUL-1997, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:BAA19521.1};
OS Pseudomonas sp.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=306 {ECO:0000313|EMBL:BAA19521.1};
RN [1] {ECO:0000313|EMBL:BAA19521.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=E6 {ECO:0000313|EMBL:BAA19521.1};
RX PubMed=9546154;
RA Watanabe K., Yamamoto S., Hino S., Harayama S.;
RT "Population dynamics of phenol-degrading bacteria in activated sludge
RT determined by gyrB-targeted quantitative PCR.";
RL Appl. Environ. Microbiol. 64:1203-1209(1998).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; AB002237; BAA19521.1; -; Genomic_DNA.
DR AlphaFoldDB; O05326; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR000565; Topo_IIA_B.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:BAA19521.1"
FT NON_TER 200
FT /evidence="ECO:0000313|EMBL:BAA19521.1"
SQ SEQUENCE 200 AA; 21950 MW; DC8CD5F525CFF72B CRC64;
HAGGKFNQNS YKVSGGLHGV GVSCVNALSK WLRLTVRRDG KVHQIEFAKG FVQNRLLETV
DGFEVSPMKV TGATEKRGTE VHFLPDTEIF QQNHEFHYEI LAKRLRELSF LNNGVRIRLK
DERSGKEDDF SGAGGVKGFV EFINGTKKVL HPTAFHATGT RPAESYGGIP GTEIGVEVAM
QWNDATTSRC SASPTTSRSA
//
