ID O16272_CAEEL Unreviewed; 244 AA.
AC O16272;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 13-FEB-2019, sequence version 2.
DT 24-JAN-2024, entry version 126.
DE SubName: Full=Cytochrome b561 domain-containing protein {ECO:0000313|EMBL:CCD65243.2};
GN ORFNames=CELE_F39G3.4 {ECO:0000313|EMBL:CCD65243.2}, F39G3.4
GN {ECO:0000313|EMBL:CCD65243.2, ECO:0000313|WormBase:F39G3.4};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD65243.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD65243.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD65243.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- COFACTOR:
CC Name=heme b; Xref=ChEBI:CHEBI:60344;
CC Evidence={ECO:0000256|ARBA:ARBA00001970};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; BX284605; CCD65243.2; -; Genomic_DNA.
DR PIR; T03906; T03906.
DR AlphaFoldDB; O16272; -.
DR SMR; O16272; -.
DR STRING; 6239.F39G3.4.1; -.
DR PaxDb; 6239-F39G3-4; -.
DR EnsemblMetazoa; F39G3.4.1; F39G3.4.1; WBGene00018209.
DR UCSC; F39G3.4; c. elegans.
DR AGR; WB:WBGene00018209; -.
DR WormBase; F39G3.4; CE52860; WBGene00018209; -.
DR eggNOG; KOG1619; Eukaryota.
DR GeneTree; ENSGT00950000183197; -.
DR HOGENOM; CLU_069712_3_0_1; -.
DR InParanoid; O16272; -.
DR OrthoDB; 2877457at2759; -.
DR PhylomeDB; O16272; -.
DR Reactome; R-CEL-917937; Iron uptake and transport.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00018209; Expressed in adult organism.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR CDD; cd08554; Cyt_b561; 1.
DR Gene3D; 1.20.120.1770; -; 1.
DR InterPro; IPR043205; CYB561/CYBRD1-like.
DR InterPro; IPR006593; Cyt_b561/ferric_Rdtase_TM.
DR PANTHER; PTHR10106:SF50; CYTOCHROME B561 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10106; CYTOCHROME B561-RELATED; 1.
DR Pfam; PF03188; Cytochrom_B561; 1.
DR SMART; SM00665; B561; 1.
DR PROSITE; PS50939; CYTOCHROME_B561; 1.
PE 4: Predicted;
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00022617};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022617};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..230
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..226
FT /note="Cytochrome b561"
FT /evidence="ECO:0000259|PROSITE:PS50939"
SQ SEQUENCE 244 AA; 27451 MW; 8AF3CC5724F28666 CRC64;
MSSLGYFEFA ASVTHLVGFI TVCLNGYFFN TFYNGIGWPF ELKVGSTDAR GLVEMRGKQL
HGFLMFLGFI YLQGEALLSY RVYRFTTNRV SILIHTFLHI ASIVLAVGAL FSIILTIKYT
GASHFSNIHS YLGVCLLLVY SGQLSFGFCT YLFKCTPKDY QSRLMPVHRA VGISCMVVAC
VQCCLGYNQM VSGKLSCFKD LSCANRIEYV GSLSMIFNII YTIMVVSVVI PKPWRREKET
IKIN
//
