ID O17638_CAEEL Unreviewed; 411 AA.
AC O17638;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE SubName: Full=Transmembrane protein {ECO:0000313|EMBL:CAB03938.1};
GN ORFNames=C34F6.7 {ECO:0000313|EMBL:CAB03938.1,
GN ECO:0000313|WormBase:C34F6.7}, CELE_C34F6.7
GN {ECO:0000313|EMBL:CAB03938.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB03938.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB03938.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB03938.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM129 family.
CC {ECO:0000256|ARBA:ARBA00007332}.
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DR EMBL; BX284606; CAB03938.1; -; Genomic_DNA.
DR PIR; T19728; T19728.
DR RefSeq; NP_509874.1; NM_077473.6.
DR AlphaFoldDB; O17638; -.
DR STRING; 6239.C34F6.7.1; -.
DR EPD; O17638; -.
DR PaxDb; 6239-C34F6-7; -.
DR EnsemblMetazoa; C34F6.7.1; C34F6.7.1; WBGene00007941.
DR GeneID; 181310; -.
DR KEGG; cel:CELE_C34F6.7; -.
DR UCSC; C34F6.7; c. elegans.
DR AGR; WB:WBGene00007941; -.
DR WormBase; C34F6.7; CE15676; WBGene00007941; -.
DR eggNOG; KOG3899; Eukaryota.
DR GeneTree; ENSGT00390000013284; -.
DR HOGENOM; CLU_055694_0_0_1; -.
DR InParanoid; O17638; -.
DR OMA; VDNTRMP; -.
DR OrthoDB; 2878268at2759; -.
DR PhylomeDB; O17638; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00007941; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR InterPro; IPR018801; TM129.
DR PANTHER; PTHR31322; E3 UBIQUITIN-PROTEIN LIGASE TM129; 1.
DR PANTHER; PTHR31322:SF2; E3 UBIQUITIN-PROTEIN LIGASE TM129; 1.
DR Pfam; PF10272; Tmpp129; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|EPD:O17638};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 411 AA; 48317 MW; 860B79C963B53DF4 CRC64;
MTSIKRGTWF FIFVLGVFTA ITCEFTTQLT YLHVVSHIAI LTAAHFALVF PPEELLDGLG
LTLFDLFTIL YNSRQHDFVE YAAKRVAFFH AFVAFYPCVI AAYFVHGNIL MTAADTRRFP
SVLDYPWMWF TVLFVALIAN GYYCIRIKDY KKWPIYQYYI DNPDCVNEAQ TVIADPETFR
IKLSQRSFLF VTRNFLVYTS NWRFMAVKLA DVRLQVDNTR MPMLPNQDEE ERIRSIFVKV
SFRPAYITPF TITLRQDYYR QLNEILEVPI FVPPHINVPL TFMEELKEDF IQRIASNTRV
THRVKASEKD PCFACGTEEN MVKIERSCDG QEQRVFFHDI GARFTPPCEN CICRPLWCRS
CLAQIFIGRQ NIDNVYRYEY HRGSAQCPTC RKNFCIRDVH CVDFDYISEE N
//
