ID O28653_ARCFU Unreviewed; 781 AA.
AC O28653;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE SubName: Full=Signal-transducing histidine kinase, putative {ECO:0000313|EMBL:AAB89622.1};
GN OrderedLocusNames=AF_1620 {ECO:0000313|EMBL:AAB89622.1};
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325 {ECO:0000313|EMBL:AAB89622.1, ECO:0000313|Proteomes:UP000002199};
RN [1] {ECO:0000313|EMBL:AAB89622.1, ECO:0000313|Proteomes:UP000002199}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16
RC {ECO:0000313|Proteomes:UP000002199};
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.P., Clayton R.A., Tomb J., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B., Peterson S.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L., Utterback T., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
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DR EMBL; AE000782; AAB89622.1; -; Genomic_DNA.
DR PIR; C69452; C69452.
DR AlphaFoldDB; O28653; -.
DR STRING; 224325.AF_1620; -.
DR PaxDb; 224325-AF_1620; -.
DR EnsemblBacteria; AAB89622; AAB89622; AF_1620.
DR KEGG; afu:AF_1620; -.
DR eggNOG; arCOG03799; Archaea.
DR eggNOG; arCOG06712; Archaea.
DR HOGENOM; CLU_374546_0_0_2; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR008553; DUF835.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR PANTHER; PTHR46663:SF2; GGDEF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05763; DUF835; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AAB89622.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002199};
KW Transferase {ECO:0000313|EMBL:AAB89622.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 83..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 131..182
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 287..342
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 360..412
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 430..500
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 503..555
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT COILED 167..197
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 781 AA; 89714 MW; 33FCB8773A3022EC CRC64;
MVHRELPWSG AVLLNLFAGR GRAGIETACH CDVRHDSCGN LLHGKRRKGA EGWSEASFCL
IRRLGSGSCF RPFIAGEWCA MKVFVRFVLM LTVISILSLL LGISLVEMGV PPVYYLYVVV
IVLIVSLFSA GSILEPLEEL RDAFQSVVSG EIRTVTPKST DEFGELAKAF NWMVEELRKE
KESLEESERR FRSVVEEMDG WLFELDSHYC ITFASPNFRD KFGDVQGKPV RDVLEHFPVE
KLESGKFEYE IIKDGKITPV EVIVKKDGGT YRCLARDIST RRKIERQLAF FREILEHSVD
AIVILDVDSR ITVWNRGAEM MFGYTAEEAV GKPLNFLMPK ERWQQCTENF KRAVVEGHVK
DIEAPRIRKD GEMIIVDQTL TSIHDSNGEV IGFVAIMRDI TRRKKAEIEL KNTCEELERR
TREILEVQKG LQQLASIVEN SNDAIYSVNL EGKITSWNRT AERLFGWRRD EALGMPASKL
LPEEIKGETE FIIRRIREGE SGLRFETRRL RKDGVVIDVE VTVSPLLNEM GELSGISIIT
RDISEKRQAE REAERRMLKY EVERGRVYFA DSFDTAVDVI NDLIRCGYNG RVISRRYPEV
LGIEEGNHLM LSAKKRDGTL EPDPDRIYRE ILNMPGWKNA VLLDIDYLLI KRNFEEVYEL
IQRLKDVFFV LNKGILVVCT ESELLGEREM KLLKMECCAI KSKKIEMPAE IYEILRFVYA
QNRVGERPSI KDVMTNFGIT RNTAKKRVAY LAERGLIKMI KDGRMKVLEV TEEGREVMRV
A
//
