ID O29235_ARCFU Unreviewed; 480 AA.
AC O29235;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 112.
DE SubName: Full=4-hydroxyphenylacetate-3-hydroxylase (HpaA-3) {ECO:0000313|EMBL:AAB90216.1};
GN OrderedLocusNames=AF_1027 {ECO:0000313|EMBL:AAB90216.1};
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325 {ECO:0000313|EMBL:AAB90216.1, ECO:0000313|Proteomes:UP000002199};
RN [1] {ECO:0000313|EMBL:AAB90216.1, ECO:0000313|Proteomes:UP000002199}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16
RC {ECO:0000313|Proteomes:UP000002199};
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.P., Clayton R.A., Tomb J., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B., Peterson S.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L., Utterback T., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
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DR EMBL; AE000782; AAB90216.1; -; Genomic_DNA.
DR PIR; C69378; C69378.
DR RefSeq; WP_010878527.1; NC_000917.1.
DR AlphaFoldDB; O29235; -.
DR STRING; 224325.AF_1027; -.
DR PaxDb; 224325-AF_1027; -.
DR EnsemblBacteria; AAB90216; AAB90216; AF_1027.
DR GeneID; 24794635; -.
DR KEGG; afu:AF_1027; -.
DR eggNOG; arCOG02143; Archaea.
DR HOGENOM; CLU_023920_1_0_2; -.
DR OrthoDB; 32865at2157; -.
DR PhylomeDB; O29235; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002199}.
FT DOMAIN 3..266
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 276..470
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
SQ SEQUENCE 480 AA; 53498 MW; F92C7E0C65B940AE CRC64;
MRTSEEYRQD LYKLKPNVYV RGKKVRRDSP EVSGGINVIS KTFDLVEHPD YKDLLTTKSH
ISGKRINRFT HINQSAEDLL KKQLMTRKLC RLVGGCIQRC MGCDAINGLS VATFAADTEH
GTDYHKRFLE YVKEFQERDL VAACAQTDVK GDRSKRPHQQ DDPDMYVRVV ERRSDGIVVR
GAKNCITMAA VADEIIVVPT RAMTPEDKDY SVAFAVPADT EGVKIVARTS KLRAPEGLKM
PQGEIGDDEN MIIFDDVFVP WDRVFLCGEN KYATLAAHLF ALFHRHSYTG CKPATTDMIM
GFGALIAEYN GVYEKHNIRE KLVELAATAE LVFAAGVAAA HYGQKSPAGT FIPNEVYANV
GRRHAGLNYY KELEILAELS GGLPAALPFA EDFLSEEVGP YIRKYIKRRA DVPAEHVYRC
LFGISNILCS SLGGVQAVAG VHGGGSPVME EIAIWRSYDF EKKKDIAKYL SGISEELPRD
//
