ID O29332_ARCFU Unreviewed; 414 AA.
AC O29332;
DT 01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=Molybdenum cofactor biosynthesis protein (MoeA-2) {ECO:0000313|EMBL:AAB90308.1};
GN OrderedLocusNames=AF_0930 {ECO:0000313|EMBL:AAB90308.1};
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325 {ECO:0000313|EMBL:AAB90308.1, ECO:0000313|Proteomes:UP000002199};
RN [1] {ECO:0000313|EMBL:AAB90308.1, ECO:0000313|Proteomes:UP000002199}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16
RC {ECO:0000313|Proteomes:UP000002199};
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.P., Clayton R.A., Tomb J., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B., Peterson S.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L., Utterback T., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
CC -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005046}.
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DR EMBL; AE000782; AAB90308.1; -; Genomic_DNA.
DR PIR; B69366; B69366.
DR RefSeq; WP_010878430.1; NC_000917.1.
DR AlphaFoldDB; O29332; -.
DR STRING; 224325.AF_0930; -.
DR PaxDb; 224325-AF_0930; -.
DR EnsemblBacteria; AAB90308; AAB90308; AF_0930.
DR GeneID; 1484153; -.
DR KEGG; afu:AF_0930; -.
DR eggNOG; arCOG00216; Archaea.
DR HOGENOM; CLU_010186_7_2_2; -.
DR OrthoDB; 31371at2157; -.
DR PhylomeDB; O29332; -.
DR UniPathway; UPA00344; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00887; MoeA; 1.
DR Gene3D; 3.40.980.10; MoaB/Mog-like domain; 1.
DR Gene3D; 2.40.340.10; MoeA, C-terminal, domain IV; 1.
DR Gene3D; 3.90.105.10; Molybdopterin biosynthesis moea protein, domain 2; 1.
DR Gene3D; 2.170.190.11; Molybdopterin biosynthesis moea protein, domain 3; 1.
DR InterPro; IPR036425; MoaB/Mog-like_dom_sf.
DR InterPro; IPR001453; MoaB/Mog_dom.
DR InterPro; IPR038987; MoeA-like.
DR InterPro; IPR005111; MoeA_C_domain_IV.
DR InterPro; IPR036688; MoeA_C_domain_IV_sf.
DR InterPro; IPR005110; MoeA_linker/N.
DR InterPro; IPR036135; MoeA_linker/N_sf.
DR NCBIfam; TIGR00177; molyb_syn; 1.
DR PANTHER; PTHR10192; MOLYBDOPTERIN BIOSYNTHESIS PROTEIN; 1.
DR PANTHER; PTHR10192:SF19; MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MJ0666-RELATED; 1.
DR Pfam; PF00994; MoCF_biosynth; 1.
DR Pfam; PF03454; MoeA_C; 1.
DR Pfam; PF03453; MoeA_N; 1.
DR SMART; SM00852; MoCF_biosynth; 1.
DR SUPFAM; SSF63867; MoeA C-terminal domain-like; 1.
DR SUPFAM; SSF63882; MoeA N-terminal region -like; 1.
DR SUPFAM; SSF53218; Molybdenum cofactor biosynthesis proteins; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150};
KW Reference proteome {ECO:0000313|Proteomes:UP000002199};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 301..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 188..324
FT /note="MoaB/Mog"
FT /evidence="ECO:0000259|SMART:SM00852"
SQ SEQUENCE 414 AA; 45033 MW; A8FC53EB0DBB1D9D CRC64;
MVREKGFWKR ERVDEALYRL LKKIKALETE DVSVYNLQGR VLAEDIVAGF DVPKFNRAAM
DGYAVKAEDT FGASVSNPIM LQLAGSVEIG EVPKVVVESG MAVRIMTGAM MPEGTNAVVM
LEHTRLNGNF VEVLKSVTPM KNVSRVGEDI AAGEVVFRKG EILQPQDAGV IASLGIESVR
VYRKPRVAVI TTGNELAEVG EPLEGAKIYN SNNPMICNAL LEFGFEAISL GIARDDEEEL
RNKLQKALEF DAAVITGGTS VGAKDLVPDV VGEFGEIVFH GVSMKPGMPT GAAVVEGKPV
FMLPGSPAAA LLGFYTFAIP ALYRMMNVRI IARKWSRQKG VLQGRIPSEI GVRSNVRVLW
EDGKVYPIRI SGSGILSSFV RANALLVVPE DKEGYEEGEE VEVTLLRDVT EVFE
//
