ID O45155_CAEEL Unreviewed; 848 AA.
AC O45155;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 2.
DT 27-MAR-2024, entry version 128.
DE SubName: Full=PAW domain-containing protein {ECO:0000313|EMBL:CCD62955.2};
GN ORFNames=C17B7.5 {ECO:0000313|EMBL:CCD62955.2,
GN ECO:0000313|WormBase:C17B7.5}, CELE_C17B7.5
GN {ECO:0000313|EMBL:CCD62955.2};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD62955.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD62955.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD62955.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the transglutaminase-like superfamily. PNGase
CC family. {ECO:0000256|PROSITE-ProRule:PRU00731}.
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DR EMBL; BX284605; CCD62955.2; -; Genomic_DNA.
DR PIR; G88996; G88996.
DR RefSeq; NP_001309475.1; NM_001322507.1.
DR AlphaFoldDB; O45155; -.
DR SMR; O45155; -.
DR STRING; 6239.C17B7.5.1; -.
DR PaxDb; 6239-C17B7-5; -.
DR PeptideAtlas; O45155; -.
DR EnsemblMetazoa; C17B7.5.1; C17B7.5.1; WBGene00015879.
DR GeneID; 178766; -.
DR KEGG; cel:CELE_C17B7.5; -.
DR UCSC; C17B7.5; c. elegans.
DR AGR; WB:WBGene00015879; -.
DR WormBase; C17B7.5; CE51529; WBGene00015879; -.
DR GeneTree; ENSGT00390000006540; -.
DR HOGENOM; CLU_025088_0_0_1; -.
DR InParanoid; O45155; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00015879; Expressed in material anatomical entity and 1 other cell type or tissue.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000224; F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity; IBA:GO_Central.
DR GO; GO:0006516; P:glycoprotein catabolic process; IBA:GO_Central.
DR GO; GO:0006515; P:protein quality control for misfolded or incompletely synthesized proteins; IBA:GO_Central.
DR Gene3D; 2.60.120.1020; Peptide N glycanase, PAW domain; 3.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR038680; PAW_sf.
DR InterPro; IPR006588; Peptide_N_glycanase_PAW_dom.
DR PANTHER; PTHR48352; -; 1.
DR PANTHER; PTHR48352:SF1; PAW DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF04721; PAW; 1.
DR SMART; SM00613; PAW; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 4.
DR PROSITE; PS51398; PAW; 3.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:O45155};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..270
FT /note="PAW"
FT /evidence="ECO:0000259|PROSITE:PS51398"
FT DOMAIN 429..618
FT /note="PAW"
FT /evidence="ECO:0000259|PROSITE:PS51398"
FT DOMAIN 638..837
FT /note="PAW"
FT /evidence="ECO:0000259|PROSITE:PS51398"
FT REGION 622..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 848 AA; 97545 MW; 3421D21BED96ADC7 CRC64;
MSPQDPVYSQ NDPLLLGNSN RSRSSVPWKA TAKIATVFIG ILFITSPIVF GLTGVVGKNN
EHQHSSLANE TSWNNATEYA NLKNHSTSFT EMKKSLILNQ NKNGTVADYA TFEYNVTSDE
YLRLNDDGTK IQPWIVKNIE RKVKFYYFES ISAIEQTAFI HKIEPNEDGV IYWKFELVDT
PEMFVNQVTI TMKYLYKIIN NKGKAEMCID DSLKNCSDLP KDDELMIFHP KFKTFFIGIK
MFKREDFPET GWWDTSEMGS FSVKVGSQKR FYTNLYTETG GIVEAAPRSP SSFDEKLKYI
VGINNFNMIQ NFYSHPCSFK NFAQEKDFLL GIGYLKKIIP DEDAWIYWNI NMHDDKKQLM
HLQIEILQMQ EIVNHGGIAE FCPNSLDNCM DIPTNGSLQF EKPPFDKFFI GIKMLNNMTT
NHTNLPKIDN VGSFNVNGHW RLIRRREKFE RQTEPIQLIP ESGQNYIKFT YDVINNVYSH
KNEDGSDILP TDVQSIERIV DDGNNEAFIQ QEWPDESTGY IHWVFKLKNN GKSVKKVVIK
MEGIDDILKE DAGIIEACSN YNINCTNIPT NKSLIMEYPV DMLYINVVLV ENIRLFKTDV
KDRMNVETFS IEVYWQETPE TSTATTDVSQ MTTTPRSIET TTPSTSNDTE SNQDVISTPL
LAWRQGHIDL GRISRENHVK FTYDVMRDTY SHTQLNGSSY VPYNVANIER VVDKRLNQVY
LHRNDSKKDT YLNWVFDMTI DGKVVDKLTI KVPGMEQQQL GIRASLEICL IYGYEKCIAI
PISGGLTIEY PQFSIFKIAY TCYENKEDNT DLILFKSELK EGLNVESLSV EVNWTTKGPL
TNQTTLPT
//
