ID O54848_MOUSE Unreviewed; 81 AA.
AC O54848;
DT 01-JUN-1998, integrated into UniProtKB/TrEMBL.
DT 01-JUN-1998, sequence version 1.
DT 24-JAN-2024, entry version 109.
DE SubName: Full=Glycine receptor beta-subunit {ECO:0000313|EMBL:AAC53543.1};
DE Flags: Fragment;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAC53543.1};
RN [1] {ECO:0000313|EMBL:AAC53543.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Spa/spa {ECO:0000313|EMBL:AAC53543.1};
RX PubMed=7920630; DOI=10.1038/ng0694-136;
RA Kingsmore S.F., Giros B., Suh D., Bieniarz M., Caron M.G., Seldin M.F.;
RT "Glycine receptor beta-subunit gene mutation in spastic mouse associated
RT with LINE-1 element insertion.";
RL Nat. Genet. 7:136-141(1994).
RN [2] {ECO:0000313|EMBL:AAC53543.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Spa/spa {ECO:0000313|EMBL:AAC53543.1};
RX PubMed=9430649; DOI=10.1093/emboj/17.2.590;
RA Naas T.P., DeBerardinis R.J., Moran J.V., Ostertag E.M., Kingsmore S.F.,
RA Seldin M.F., Hayashizaki Y., Martin S.L., Kazazian H.H.;
RT "An actively retrotransposing, novel subfamily of mouse L1 elements.";
RL EMBO J. 17:590-597(1998).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AF016099; AAC53543.1; -; Genomic_DNA.
DR AlphaFoldDB; O54848; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 1.
DR InterPro; IPR006202; Neur_chan_lig-bd.
DR InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR InterPro; IPR006201; Neur_channel.
DR InterPro; IPR018000; Neurotransmitter_ion_chnl_CS.
DR PANTHER; PTHR18945:SF29; GLYCINE RECEPTOR SUBUNIT BETA; 1.
DR PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR Pfam; PF02931; Neur_chan_LBD; 1.
DR SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 1.
DR PROSITE; PS00236; NEUROTR_ION_CHANNEL; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000313|EMBL:AAC53543.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692}.
FT DOMAIN 4..72
FT /note="Neurotransmitter-gated ion-channel ligand-binding"
FT /evidence="ECO:0000259|Pfam:PF02931"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAC53543.1"
FT NON_TER 81
FT /evidence="ECO:0000313|EMBL:AAC53543.1"
SQ SEQUENCE 81 AA; 9480 MW; 0C06C6856E098C2D CRC64;
DVLVSMSFRL SITLSCPLDL TLFPMDTQRC KMQLESFGYT TDDLRFIWQS GDPVQLEKIA
LPQFDIKKED IEYGNCTKYY K
//
