ID O59099_PYRHO Unreviewed; 147 AA.
AC O59099;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 01-AUG-1998, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE RecName: Full=Na+/H+ antiporter MnhB subunit-related protein domain-containing protein {ECO:0000259|Pfam:PF04039};
GN OrderedLocusNames=PH1429 {ECO:0000313|EMBL:BAA30536.1};
OS Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS 100139 / OT-3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=70601 {ECO:0000313|EMBL:BAA30536.1, ECO:0000313|Proteomes:UP000000752};
RN [1] {ECO:0000313|EMBL:BAA30536.1, ECO:0000313|Proteomes:UP000000752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3
RC {ECO:0000313|Proteomes:UP000000752};
RX PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA Otuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Nakamura Y.,
RA Robb T.F., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT "Complete sequence and gene organization of the genome of a hyper-
RT thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL DNA Res. 5:55-76(1998).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; BA000001; BAA30536.1; -; Genomic_DNA.
DR PIR; H71016; H71016.
DR RefSeq; WP_010885513.1; NC_000961.1.
DR AlphaFoldDB; O59099; -.
DR STRING; 70601.gene:9378406; -.
DR DNASU; 1443751; -.
DR EnsemblBacteria; BAA30536; BAA30536; BAA30536.
DR GeneID; 1443751; -.
DR KEGG; pho:PH1429; -.
DR eggNOG; arCOG03079; Archaea.
DR OrthoDB; 19265at2157; -.
DR Proteomes; UP000000752; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007182; MnhB.
DR PANTHER; PTHR33932; NA(+)/H(+) ANTIPORTER SUBUNIT B; 1.
DR PANTHER; PTHR33932:SF4; NA(+)_H(+) ANTIPORTER SUBUNIT B1; 1.
DR Pfam; PF04039; MnhB; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..133
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 147 AA; 15552 MW; 99B85E43E2F8ED66 CRC64;
MSDMGVIVKT NARALIPLIG VFGSYIILHG HLTPGGGFQG GATIVGTALL FLIAFGVDEA
KKRINKDLYS ALEGIGGLVF LGAAMLGLSV AFFYNILWHK GPLFNGRPGT LLSAGFLPIM
NLGVGLKVFT GLVSAVFALA LFRRWKE
//
