ID O62387_CAEEL Unreviewed; 250 AA.
AC O62387;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 01-AUG-1998, sequence version 1.
DT 27-MAR-2024, entry version 140.
DE SubName: Full=t-SNARE coiled-coil homology domain-containing protein {ECO:0000313|EMBL:CAB10725.1};
GN Name=syx-17 {ECO:0000313|EMBL:CAB10725.1,
GN ECO:0000313|WormBase:VF39H2L.1};
GN ORFNames=CELE_VF39H2L.1 {ECO:0000313|EMBL:CAB10725.1}, VF39H2L.1
GN {ECO:0000313|WormBase:VF39H2L.1};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB10725.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB10725.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB10725.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063}.
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DR EMBL; BX284601; CAB10725.1; -; Genomic_DNA.
DR PIR; T26010; T26010.
DR RefSeq; NP_492342.1; NM_059941.3.
DR AlphaFoldDB; O62387; -.
DR SMR; O62387; -.
DR IntAct; O62387; 1.
DR STRING; 6239.VF39H2L.1.1; -.
DR EPD; O62387; -.
DR PaxDb; 6239-VF39H2L-1; -.
DR EnsemblMetazoa; VF39H2L.1.1; VF39H2L.1.1; WBGene00012150.
DR GeneID; 172663; -.
DR KEGG; cel:CELE_VF39H2L.1; -.
DR UCSC; VF39H2L.1; c. elegans.
DR AGR; WB:WBGene00012150; -.
DR WormBase; VF39H2L.1; CE18300; WBGene00012150; syx-17.
DR eggNOG; KOG0811; Eukaryota.
DR GeneTree; ENSGT01000000214440; -.
DR HOGENOM; CLU_1112156_0_0_1; -.
DR InParanoid; O62387; -.
DR OMA; VHEQHDV; -.
DR OrthoDB; 200189at2759; -.
DR PhylomeDB; O62387; -.
DR Reactome; R-CEL-204005; COPII-mediated vesicle transport.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00012150; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR GO; GO:0000421; C:autophagosome membrane; IBA:GO_Central.
DR GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0031201; C:SNARE complex; IBA:GO_Central.
DR GO; GO:0005484; F:SNAP receptor activity; IBA:GO_Central.
DR GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR GO; GO:0006887; P:exocytosis; IBA:GO_Central.
DR GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR GO; GO:0048278; P:vesicle docking; IBA:GO_Central.
DR GO; GO:0006906; P:vesicle fusion; IBA:GO_Central.
DR Gene3D; 1.20.5.110; -; 1.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; SYNTAXIN; 1.
DR PANTHER; PTHR19957:SF413; T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05739; SNARE; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF47661; t-snare proteins; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|EPD:O62387};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 129..191
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT COILED 160..194
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 250 AA; 27488 MW; 9626894AD7B1E275 CRC64;
MYEKTANRQL GELRVLQRIA LQGGLRDTPA LRDSIAAYEK DLEDGLRGIL TVRGELHDSR
QENEFDSIID PIRQQIKTLL NVTRSLPAVN LPGSNPFEQA TEDDNPYEME SRRYLRETTL
KDNELRQLAD DMKERAEATV KIEKDMADLE KIFQELGRIV HEQHDVVDSI EEQVERATED
VKRGNENLKK AVKSKAAKAP LYAGVVGGLA VGGPVGLAAG SAIAGIAAGV GGLVATIYTG
KFFKRSATSD
//
