ID O64731_ARATH Unreviewed; 331 AA.
AC O64731;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 01-AUG-1998, sequence version 1.
DT 27-MAR-2024, entry version 166.
DE SubName: Full=Mitochondrial substrate carrier family protein {ECO:0000313|EMBL:AEC08353.1};
DE SubName: Full=Putative mitochondrial carrier protein {ECO:0000313|EMBL:AAC16956.1};
GN Name=MIT1 {ECO:0000313|TAIR:AT2G30160};
GN OrderedLocusNames=At2g30160 {ECO:0000313|Araport:AT2G30160,
GN ECO:0000313|EMBL:AEC08353.1};
GN ORFNames=T27E13.10 {ECO:0000313|EMBL:AEC08353.1}, T27E13_10
GN {ECO:0000313|EMBL:AEC08353.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:AAC16956.1};
RN [1] {ECO:0000313|EMBL:AEC08353.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S., Shea T.P., Benito M.I., Town C.D.,
RA Fujii C.Y., Mason T., Bowman C.L., Barnstead M., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2] {ECO:0000313|EMBL:AAC16956.1}
RP NUCLEOTIDE SEQUENCE.
RA Rounsley S.D., Lin X., Ketchum K.A., Crosby M.L., Brandon R.C., Sykes S.M.,
RA Kaul S., Mason T.M., Kerlavage A.R., Adams M.D., Somerville C.R.,
RA Venter J.C.;
RL Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AAL36333.1}
RP NUCLEOTIDE SEQUENCE.
RA Yamada K., Liu S.X., Sakano H., Pham P.K., Banh J., Chung M.K.,
RA Goldsmith A.D., Lee J.M., Quach H.L., Toriumi M., Yu G., Bowser L.,
RA Carninci P., Chen H., Cheuk R., Hayashizaki Y., Ishida J., Jones T.,
RA Kamiya A., Karlin-Neumann G., Kawai J., Kim C., Lam B., Lin J., Miranda M.,
RA Narusaka M., Nguyen M., Palm C.J., Sakurai T., Satou M., Seki M., Shinn P.,
RA Southwick A., Shinozaki K., Davis R.W., Ecker J.R., Theologis A.;
RT "Arabidopsis Full Length cDNA Clones.";
RL Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AAC16956.1}
RP NUCLEOTIDE SEQUENCE.
RA Town C.D., Kaul S.;
RL Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:AAM20034.1}
RP NUCLEOTIDE SEQUENCE.
RA Yamada K., Banh J., Chan M.M., Chang C.H., Chang E., Dale J.M., Deng J.M.,
RA Goldsmith A.D., Lee J.M., Onodera C.S., Quach H.L., Tang C., Toriumi M.,
RA Wu H.C., Yamamura Y., Yu G., Bowser L., Carninci P., Chen H., Cheuk R.,
RA Hayashizaki Y., Ishida J., Jones T., Kamiya A., Karlin-Neumann G.,
RA Kawai J., Kim C., Lam B., Lin J., Meyers M.C., Miranda M., Narusaka M.,
RA Nguyen M., Palm C.J., Sakurai T., Satou M., Seki M., Shinn P.,
RA Southwick A., Shinozaki K., Davis R.W., Ecker J.R., Theologis A.;
RT "Arabidopsis Open Reading Frame (ORF) Clones.";
RL Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:AEC08353.1}
RP NUCLEOTIDE SEQUENCE.
RG TAIR;
RA Swarbreck D., Lamesch P., Wilks C., Huala E.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:AEC08353.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheng C.-Y., Chan A.P., Schobel S., Kim M., Ferlanti E.S.,
RA Belyaeva I., Rosen B.D., Micklem G., Miller J.R., Vaughn M., Town C.D.;
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375, ECO:0000256|RuleBase:RU000488}.
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DR EMBL; AC004165; AAC16956.1; -; Genomic_DNA.
DR EMBL; AY063977; AAL36333.1; -; mRNA.
DR EMBL; AY096394; AAM20034.1; -; mRNA.
DR EMBL; CP002685; AEC08353.1; -; Genomic_DNA.
DR PIR; T00582; T00582.
DR RefSeq; NP_180577.1; NM_128571.3.
DR AlphaFoldDB; O64731; -.
DR SMR; O64731; -.
DR IntAct; O64731; 6.
DR STRING; 3702.O64731; -.
DR PaxDb; 3702-AT2G30160-1; -.
DR ProteomicsDB; 185435; -.
DR DNASU; 817568; -.
DR EnsemblPlants; AT2G30160.1; AT2G30160.1; AT2G30160.
DR GeneID; 817568; -.
DR Gramene; AT2G30160.1; AT2G30160.1; AT2G30160.
DR KEGG; ath:AT2G30160; -.
DR Araport; AT2G30160; -.
DR TAIR; AT2G30160; MIT1.
DR eggNOG; KOG0760; Eukaryota.
DR HOGENOM; CLU_015166_3_1_1; -.
DR OMA; CVRTVTH; -.
DR OrthoDB; 5481380at2759; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O64731; baseline and differential.
DR GO; GO:0031966; C:mitochondrial membrane; IDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IGI:TAIR.
DR GO; GO:0045333; P:cellular respiration; IGI:TAIR.
DR GO; GO:0048250; P:iron import into the mitochondrion; IGI:TAIR.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 2.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45758:SF22; MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN; 1.
DR PANTHER; PTHR45758; MITOFERRIN-1-RELATED; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Proteomics identification {ECO:0007829|PeptideAtlas:O64731,
KW ECO:0007829|ProteomicsDB:O64731};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU000488}.
FT REPEAT 36..123
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 130..214
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 230..320
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
SQ SEQUENCE 331 AA; 35961 MW; A0DE93084BBC8BC3 CRC64;
MATEATTKFP ESDLRPIPQP PDFHPAIIVP AQNTTLKFWQ LMVAGSIAGS VEHMAMFPVD
TVKTHMQALR SCPIKPIGIR QAFRSIIKTD GPSALYRGIW AMGLGAGPAH AVYFSFYEVS
KKFLSGGNPN NSAAHAISGV FATISSDAVF TPMDMVKQRL QIGNGTYKGV WDCIKRVTRE
EGFGAFYASY RTTVLMNAPF TAVHFTTYEA VKRGLREMLP EHAVGAEDEE GWLIYATAGA
AAGGLAAAVT TPLDVVKTQL QCQGVCGCDR FKSSSISDVF RTIVKKDGYR GLARGWLPRM
LFHAPAAAIC WSTYETVKSF FQDLNGEANA A
//
