ID KNOSC_ORYSI Reviewed; 355 AA.
AC O65034; A2YHU1;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-JAN-2009, sequence version 2.
DT 27-MAR-2024, entry version 128.
DE RecName: Full=Homeobox protein knotted-1-like 12;
DE AltName: Full=Homeobox protein HOS3;
DE AltName: Full=Homeobox protein OSH15;
DE AltName: Full=Homeobox protein knotted-1-like 3;
DE Short=Oskn3;
GN Name=OSH15; Synonyms=HOS3; ORFNames=OsI_023884;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. IR58;
RX PubMed=10080693; DOI=10.1023/a:1006153506868;
RA Postma-Haarsma A.D., Verwoert I.I.G., Stronk O.P., Koster J.,
RA Lamers G.E.M., Hoge J.H., Meijer A.H.;
RT "Characterization of the KNOX class homeobox genes Oskn2 and Oskn3
RT identified in a collection of cDNA libraries covering the early stages of
RT rice embryogenesis.";
RL Plant Mol. Biol. 39:257-271(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18430022; DOI=10.1111/j.1742-4658.2008.06424.x;
RA Jain M., Tyagi A.K., Khurana J.P.;
RT "Genome-wide identification, classification, evolutionary expansion and
RT expression analyses of homeobox genes in rice.";
RL FEBS J. 275:2845-2861(2008).
CC -!- FUNCTION: Probable transcription factor that may be involved in shoot
CC formation during embryogenesis. {ECO:0000269|PubMed:10080693}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108,
CC ECO:0000255|PROSITE-ProRule:PRU00559}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the embryo at 4 days after
CC pollination (DAP) in the ventral and basal part of the embryo including
CC the initial of the shoot apical meristem (SAM). At 5 DAP, expressed at
CC the ventral side of the embryo, but the expression within SAM is down-
CC regulated. At 7 DAP, expression is restricted to the boundaries between
CC the embryonic organs, between the scutellum and the coleoptile, the
CC coleoptile and the second leaf primordium, the shoot apical meristem
CC and the first leaf primordium, the first leaf primordium and the
CC coleoptile, the coleoptile and the epiblast and at the tip of the
CC epiblast, but not in the leaf primordia. {ECO:0000269|PubMed:10080693}.
CC -!- SIMILARITY: Belongs to the TALE/KNOX homeobox family.
CC {ECO:0000255|PROSITE-ProRule:PRU00559}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC32818.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AF050181; AAC32818.1; ALT_SEQ; mRNA.
DR EMBL; CM000132; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; T02785; T02785.
DR AlphaFoldDB; O65034; -.
DR SMR; O65034; -.
DR STRING; 39946.O65034; -.
DR EnsemblPlants; BGIOSGA025091-TA; BGIOSGA025091-PA; BGIOSGA025091.
DR Gramene; BGIOSGA025091-TA; BGIOSGA025091-PA; BGIOSGA025091.
DR HOGENOM; CLU_040111_0_0_1; -.
DR OMA; QRANFIC; -.
DR Proteomes; UP000007015; Chromosome 7.
DR ExpressionAtlas; O65034; differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR005539; ELK_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR008422; Homeobox_KN_domain.
DR InterPro; IPR005540; KNOX1.
DR InterPro; IPR005541; KNOX2.
DR PANTHER; PTHR11850:SF102; HOMEOBOX PROTEIN HOMOTHORAX; 1.
DR PANTHER; PTHR11850; HOMEOBOX PROTEIN TRANSCRIPTION FACTORS; 1.
DR Pfam; PF03789; ELK; 1.
DR Pfam; PF05920; Homeobox_KN; 1.
DR Pfam; PF03790; KNOX1; 1.
DR Pfam; PF03791; KNOX2; 1.
DR SMART; SM01188; ELK; 1.
DR SMART; SM00389; HOX; 1.
DR SMART; SM01255; KNOX1; 1.
DR SMART; SM01256; KNOX2; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51213; ELK; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Homeobox; Nucleus; Reference proteome.
FT CHAIN 1..355
FT /note="Homeobox protein knotted-1-like 12"
FT /id="PRO_0000360016"
FT DOMAIN 236..256
FT /note="ELK"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00559"
FT DNA_BIND 257..320
FT /note="Homeobox; TALE-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 52..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..233
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 355 AA; 38590 MW; 9BE7C380611865E2 CRC64;
MDQSFGNLGG GGGAGGSGKA AASSFLQLPL STAAAATAYY GTPLALHQAA AAAGPSQYHG
HGHPHHGGGH HHSKHGGAGG GEISAAEAES IKAKIMAHPQ YSALLAAYLD CQKVGAPPEV
LERLTATAAK LDARPPGRHD ARDPELDQFM EAYCNMLAKY REELTRPIDE AMEFLKRVES
QLDTIAGGAH GGGAGSARLL LADGKSECVG SSEDDMDPSG RENEPPEIDP RAEDKELKFQ
LLKKYSGYLS SLRQEFSKKK KKGKLPKEAR QKLLHWWELH YKWPYPSETE KIALAESTGL
DQKQINNWFI NQRKRHWKPS EDMPFVMMEG FHPQNAAALY MDGPFMADGM YRLGS
//
