ID O66040_SALTM Unreviewed; 240 AA.
AC O66040; A0A0F7DIT7; A0A0M2J1E9; Q7CQB6;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 01-AUG-1998, sequence version 1.
DT 27-MAR-2024, entry version 178.
DE SubName: Full=SdiA {ECO:0000313|EMBL:AAC08299.1, ECO:0000313|EMBL:AKH07600.1};
DE SubName: Full=LuxR family transcriptional regulator {ECO:0000313|EMBL:KTZ14684.1};
DE SubName: Full=Transcriptional regulator SdiA {ECO:0000313|EMBL:EBU9274824.1};
GN Name=sdiA {ECO:0000313|EMBL:AAC08299.1};
GN ORFNames=AAB27_10445 {ECO:0000313|EMBL:ECV8761309.1}, AU613_18200
GN {ECO:0000313|EMBL:MIT50789.1}, AVC05_12305
GN {ECO:0000313|EMBL:ECY5342009.1}, B1P38_18855
GN {ECO:0000313|EMBL:ECU8355601.1}, CE70_02180
GN {ECO:0000313|EMBL:ECE0294012.1}, CFF59_03685
GN {ECO:0000313|EMBL:EDI6664369.1}, CVR97_18520
GN {ECO:0000313|EMBL:PJH60617.1}, DD95_03030
GN {ECO:0000313|EMBL:KTZ14684.1}, DMO92_22695
GN {ECO:0000313|EMBL:EBU9274824.1}, DPS76_09925
GN {ECO:0000313|EMBL:EBW5462756.1}, DRM14_20015
GN {ECO:0000313|EMBL:MLP87566.1}, DU071_16970
GN {ECO:0000313|EMBL:EBY1703604.1}, E0935_25360
GN {ECO:0000313|EMBL:ECF1546548.1}, EER35_11865
GN {ECO:0000313|EMBL:EBZ6921666.1}, F3R12_16835
GN {ECO:0000313|EMBL:ECW0641489.1}, GB466_20985
GN {ECO:0000313|EMBL:HAB0973007.1}, SE14_02092
GN {ECO:0000313|EMBL:AKH07600.1};
OS Salmonella typhimurium.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90371 {ECO:0000313|EMBL:AAC08299.1};
RN [1] {ECO:0000313|EMBL:AAC08299.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=14028 {ECO:0000313|EMBL:AAC08299.1};
RA Ahmer B.M.M., Timmers C., Devore B., Heffron F.;
RL Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AAC08299.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=14028 {ECO:0000313|EMBL:AAC08299.1};
RX PubMed=9495757;
RA Ahmer B.M., van Reeuwijk J., Timmers C.D., Valentine P.J., Heffron F.;
RT "Salmonella typhimurium encodes an SdiA homolog, a putative quorum sensor
RT of the LuxR family, that regulates genes on the virulence plasmid.";
RL J. Bacteriol. 180:1185-1193(1998).
RN [3] {ECO:0000313|EMBL:KTZ14684.1, ECO:0000313|Proteomes:UP000054461}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CVM N32045 {ECO:0000313|EMBL:KTZ14684.1,
RC ECO:0000313|Proteomes:UP000054461};
RA Chen Y., Folster J., Ayers S., Kabera C., Li C., Mukherjee S., Lam C.,
RA Zhao S., McDermott P.;
RT "Salmonella Genotype and Phenotype Association.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AKH07600.1, ECO:0000313|Proteomes:UP000034636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YU39 {ECO:0000313|EMBL:AKH07600.1,
RC ECO:0000313|Proteomes:UP000034636};
RX PubMed=26089426;
RA Calva E., Silva C., Zaidi M.B., Sanchez-Flores A., Estrada K., Silva G.G.,
RA Soto-Jimenez L.M., Wiesner M., Fernandez-Mora M., Edwards R.A., Vinuesa P.;
RT "Complete Genome Sequencing of a Multidrug-Resistant and Human-Invasive
RT Salmonella enterica Serovar Typhimurium Strain of the Emerging Sequence
RT Type 213 Genotype.";
RL Genome Announc. 3:e00663-15(2015).
RN [5] {ECO:0000313|EMBL:PJH60617.1, ECO:0000313|Proteomes:UP000228538}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N029 {ECO:0000313|EMBL:PJH60617.1,
RC ECO:0000313|Proteomes:UP000228538};
RA Sanad Y., Khajanchi B., Deck J., Cox J., Thaker R., Han J., Nayak R.,
RA Foley S.;
RT "Characterization of the Virulence Potential of Salmonella enterica
RT Isolates Carrying Incompatibility Group FIB Plasmids using Caco-2
RT Intestinal Epithelial Cells.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:HAB0973007.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Salmonella enterica {ECO:0000313|EMBL:HAB0973007.1};
RX PubMed=30286803;
RA Souvorov A., Agarwala R., Lipman D.J.;
RT "SKESA: strategic k-mer extension for scrupulous assemblies.";
RL Genome Biol. 19:153-153(2018).
RN [7] {ECO:0000313|EMBL:EDI6664369.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PNUSAS008736 {ECO:0000313|EMBL:ECU8355601.1}, and PNUSAS016739
RC {ECO:0000313|EMBL:EDI6664369.1};
RG PulseNet: The National Subtyping Network for Foodborne Disease Surveillance;
RA Tarr C.L., Trees E., Katz L.S., Carleton-Romer H.A., Stroika S.,
RA Kucerova Z., Roache K.F., Sabol A.L., Besser J., Gerner-Smidt P.;
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
RN [8] {ECO:0000313|EMBL:EBZ6921666.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=265852 {ECO:0000313|EMBL:ECF1546548.1}, 29290
RC {ECO:0000313|EMBL:MIT50789.1}, 356083 {ECO:0000313|EMBL:EBY1703604.1},
RC 422529 {ECO:0000313|EMBL:EBW5462756.1}, 425567
RC {ECO:0000313|EMBL:MLP87566.1}, 43916 {ECO:0000313|EMBL:ECY5342009.1},
RC 488670 {ECO:0000313|EMBL:EBU9274824.1}, 632340
RC {ECO:0000313|EMBL:EBZ6921666.1}, and 86846
RC {ECO:0000313|EMBL:ECV8761309.1};
RA Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [9] {ECO:0000313|EMBL:ECW0641489.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AUSMDU00020735 {ECO:0000313|EMBL:ECW0641489.1}, and
RC VA_WGS-00080 {ECO:0000313|EMBL:ECE0294012.1,
RC ECO:0000313|Proteomes:UP000338496};
RG GenomeTrakr network: Whole genome sequencing for foodborne pathogen traceback;
RL Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
RN [10] {ECO:0000313|EMBL:HAB0973007.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Salmonella enterica {ECO:0000313|EMBL:HAB0973007.1};
RG NCBI Pathogen Detection Project;
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; U88651; AAC08299.1; -; Genomic_DNA.
DR EMBL; CP011428; AKH07600.1; -; Genomic_DNA.
DR EMBL; AAHDPU010000033; EBU9274824.1; -; Genomic_DNA.
DR EMBL; AAHIPE010000008; EBW5462756.1; -; Genomic_DNA.
DR EMBL; AAHNIA010000035; EBY1703604.1; -; Genomic_DNA.
DR EMBL; AAHRYM010000012; EBZ6921666.1; -; Genomic_DNA.
DR EMBL; AAIGQE010000001; ECE0294012.1; -; Genomic_DNA.
DR EMBL; AAIKGB010000052; ECF1546548.1; -; Genomic_DNA.
DR EMBL; AAKRET010000021; ECU8355601.1; -; Genomic_DNA.
DR EMBL; AAKUOT010000017; ECV8761309.1; -; Genomic_DNA.
DR EMBL; AAKVET010000013; ECW0641489.1; -; Genomic_DNA.
DR EMBL; AALDNI010000023; ECY5342009.1; -; Genomic_DNA.
DR EMBL; AAMLUT010000001; EDI6664369.1; -; Genomic_DNA.
DR EMBL; DAAFPQ010000021; HAB0973007.1; -; Genomic_DNA.
DR EMBL; JYVU01000008; KTZ14684.1; -; Genomic_DNA.
DR EMBL; RSUA01000039; MIT50789.1; -; Genomic_DNA.
DR EMBL; RVDJ01000024; MLP87566.1; -; Genomic_DNA.
DR EMBL; PHGX01000056; PJH60617.1; -; Genomic_DNA.
DR RefSeq; WP_001157166.1; NZ_WXYU01000012.1.
DR SMR; O66040; -.
DR KEGG; seni:CY43_10275; -.
DR PATRIC; fig|59201.158.peg.2128; -.
DR PATRIC; fig|90371.1185.peg.2139; -.
DR eggNOG; COG2197; Bacteria.
DR OMA; NHTVDWY; -.
DR Proteomes; UP000034636; Chromosome.
DR Proteomes; UP000054461; Unassembled WGS sequence.
DR Proteomes; UP000228538; Unassembled WGS sequence.
DR Proteomes; UP000338496; Unassembled WGS sequence.
DR Proteomes; UP000839581; Unassembled WGS sequence.
DR Proteomes; UP000839595; Unassembled WGS sequence.
DR Proteomes; UP000839616; Unassembled WGS sequence.
DR Proteomes; UP000839617; Unassembled WGS sequence.
DR Proteomes; UP000839905; Unassembled WGS sequence.
DR Proteomes; UP000839908; Unassembled WGS sequence.
DR Proteomes; UP000839909; Unassembled WGS sequence.
DR Proteomes; UP000839911; Unassembled WGS sequence.
DR Proteomes; UP000839914; Unassembled WGS sequence.
DR Proteomes; UP000839915; Unassembled WGS sequence.
DR Proteomes; UP000885258; Unassembled WGS sequence.
DR Proteomes; UP000885385; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.30.450.80; Transcription factor LuxR-like, autoinducer-binding domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR005143; TF_LuxR_autoind-bd_dom.
DR InterPro; IPR036693; TF_LuxR_autoind-bd_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR44688; -; 1.
DR PANTHER; PTHR44688:SF13; REGULATORY PROTEIN SDIA; 1.
DR Pfam; PF03472; Autoind_bind; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF75516; Pheromone-binding domain of LuxR-like quorum-sensing transcription factors; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:AKH07600.1}.
FT DOMAIN 173..238
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 240 AA; 28145 MW; D3F875ADA44BF916 CRC64;
MQENDFFTWR RAMLLRFQEM AAAEDVYTEL QYQTQRLEFD YYALCVRHPV PFTRPKISLR
TTYPPAWVTH YQSENYFAID PVLKPENFRQ GHLHWDDVLF HEAKAMWDAA QRFGLRRGVT
QCVMLPNRAL GFLSFSRSSL RCSSFTYDEV ELRLQLLARE SLSALTRFED DMVMAPEMRF
SKREKEILKW TAEGKTSSEI AIILSISENT VNFHQKNMQK KFNAPNKTQI ACYAAATGLI
//
