ID O70414_RAT Unreviewed; 230 AA.
AC O70414;
DT 01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT 01-AUG-1998, sequence version 1.
DT 22-FEB-2023, entry version 94.
DE SubName: Full=Putative pheromone receptor V2R2B {ECO:0000313|EMBL:AAC08417.1};
DE Flags: Fragment;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116 {ECO:0000313|EMBL:AAC08417.1};
RN [1] {ECO:0000313|EMBL:AAC08417.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Vomeronasal neurons {ECO:0000313|EMBL:AAC08417.1};
RX PubMed=9292726; DOI=10.1016/S0896-6273(00)80946-0;
RA Ryba N.J.P., Tirindelli R.;
RT "A new multigene family of putative pheromone receptors.";
RL Neuron 19:371-379(1997).
RN [2] {ECO:0000313|EMBL:AAC08417.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Vomeronasal neurons {ECO:0000313|EMBL:AAC08417.1};
RA Ryba N.J.P., Tirindelli R.;
RL Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AF053990; AAC08417.1; -; mRNA.
DR AlphaFoldDB; O70414; -.
DR UCSC; RGD:735122; rat.
DR PhylomeDB; O70414; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF530; VOMERONASAL 2 RECEPTOR 128-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:AAC08417.1};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..194
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AAC08417.1"
SQ SEQUENCE 230 AA; 25703 MW; 274EEF5F4D72F404 CRC64;
NWTCMARQVT LALGFCLCLS SILGKTISLF FAYRISKSKT RLISMHPIFR KLIVLICVVG
EIGVCTAYLM LKPPRMVKNI EPQNVKIIFE CNEGSIEFLC SIFAFDVLLA LLCFLTTFVA
RKLPDNYYEG KCITFGMLVF FIVWISFVPA YLSTKGKFKV AVEIFAILAS SYGLLGCIFL
PKCFIILLRP KRNTDETVGG RVPTVDRSIQ LASTSVSSEL NTTVSTVLDE
//
