ID O76120_PLAFA Unreviewed; 568 AA.
AC O76120;
DT 01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1998, sequence version 1.
DT 22-FEB-2023, entry version 51.
DE SubName: Full=Thrombospondin-related protein {ECO:0000313|EMBL:BAA31195.1};
DE Flags: Fragment;
OS Plasmodium falciparum (malaria parasite P. falciparum).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=5833 {ECO:0000313|EMBL:BAA31195.1};
RN [1] {ECO:0000313|EMBL:BAA31195.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=9657338; DOI=10.1016/S0166-6851(98)00004-8;
RA Jongwutiwes S., Putaporntip C., Kanbara H., Tanabe K.;
RT "Variation in the thrombospondin-related adhesive protein (TRAP) gene of
RT Plasmodium falciparum from Thai field isolates.";
RL Mol. Biochem. Parasitol. 92:349-353(1998).
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DR EMBL; AB006359; BAA31195.1; -; Genomic_DNA.
DR AlphaFoldDB; O76120; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01471; vWA_micronemal_protein; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR16059; ANTHRAX TOXIN RECEPTOR; 1.
DR PANTHER; PTHR16059:SF25; THROMBOSPONDIN-RELATED ANONYMOUS PROTEIN; 1.
DR Pfam; PF00090; TSP_1; 1.
DR Pfam; PF00092; VWA; 1.
DR SMART; SM00209; TSP1; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50092; TSP1; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..568
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004159753"
FT DOMAIN 48..234
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 279..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 534..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..366
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..503
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..568
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 568
FT /evidence="ECO:0000313|EMBL:BAA31195.1"
SQ SEQUENCE 568 AA; 64735 MW; D90ED099B5FC6E15 CRC64;
MNHLGNVKYL VIVFLIFFDL FLVNGRDVQN NIVDEIKYRE EVCNDEVDLY LLMDCSGSYR
RHNWVNHAVP LAMKLIQQLN LNESAIHLYL NDFSNNAREI IRLHSDASKN KEKALIIIKS
LLNTNLPYGR TNLTDALLQV RKHLNDRINR ENANQLVVIL TDGIPDSIQD SLKESRKLND
RGVKIAVFGI GQGINVAFNR FLVGCHPSDG KCNLYADSAW ENVKNVIGPF MKAVCVEVEK
TASCGVWDEW SPCSVTCGKG TRSRKREILH EGCTSELQEQ CEEERCPPKR EPLDVPHEPE
DDQPRPRGDN FVVEKPEENI IDNNPQEPSP NPEEGKGENP NGFDLDENPE NPPNPPNPPN
PPNPDIPEQD QIYLKIQKKK YLLMFQKIQK TIEKENFDIP KKPENKHDNQ NNLPNDKSDR
YIPYSPLPPK VLDNERKQSD PQSQDNNGNR HVPNSEDRET RPHGRNNENR SYNRKHNNTP
KHPEREEHEK PDNNKKKGES DNKYKIAGGI AGGLALLASA GLAYKFVVPG AATPYAGEPA
PFDETLGEED KDLDEPEQFR LPEENEWN
//
