ID O77381_PLAF7 Unreviewed; 161 AA.
AC O77381;
DT 01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2000, sequence version 2.
DT 27-MAR-2024, entry version 154.
DE SubName: Full=40S ribosomal protein S11, putative {ECO:0000313|EMBL:CAB11137.2};
GN ORFNames=PF3D7_0317600 {ECO:0000313|EMBL:CAB11137.2};
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CAB11137.2, ECO:0000313|Proteomes:UP000001450};
RN [1] {ECO:0000313|EMBL:CAB11137.2, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=10448855; DOI=10.1038/22964;
RA Bowman S., Lawson D., Basham D., Brown D., Chillingworth T., Churcher C.M.,
RA Craig A., Davies R.M., Devlin K., Feltwell T., Gentles S., Gwilliam R.,
RA Hamlin N., Harris D., Holroyd S., Hornsby T., Horrocks P., Jagels K.,
RA Jassal B., Kyes S., McLean J., Moule S., Mungall K., Murphy L., Oliver K.,
RA Quail M.A., Rajandream M.-A., Rutter S., Skelton J., Squares R.,
RA Squares S., Sulston J.E., Whitehead S., Woodward J.R., Newbold C.,
RA Barrell B.G.;
RT "The complete nucleotide sequence of chromosome 3 of Plasmodium
RT falciparum.";
RL Nature 400:532-538(1999).
RN [2] {ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., Chan M.S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [3] {ECO:0000313|EMBL:CAB11137.2, ECO:0000313|Proteomes:UP000001450}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX PubMed=12368867; DOI=10.1038/nature01095;
RA Hall N., Pain A., Berriman M., Churcher C., Harris B., Harris D.,
RA Mungall K., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA Christodoulou Z., Clark L., Clark R., Corto C., Cronin A., Davies R.,
RA Davies P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James D.,
RA Johnson D., Kerhornou A., Knight A., Kontfortov B., Keyes S., Larke N.,
RA Lawson D., Lennard N., Line A., Maddison M., McLean J., Mooney P.,
RA Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA Rabbinowitsch E., Rajandream M-A., Rutter S., Rutherford K.M., Sanders M.,
RA Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.,
RA Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL Nature 419:527-531(2002).
RN [4] {ECO:0007829|PDB:3J7A, ECO:0007829|PDB:6OKK}
RP STRUCTURE BY ELECTRON MICROSCOPY (3.20 ANGSTROMS).
RX PubMed=24913268; DOI=10.7554/eLife.03080;
RA Wong W., Bai X.C., Brown A., Fernandez I.S., Hanssen E., Condron M.,
RA Tan Y.H., Baum J., Scheres S.H.;
RT "Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the
RT anti-protozoan drug emetine.";
RL Elife 3:e03080-e03080(2014).
RN [5] {ECO:0007829|PDB:3JBN, ECO:0007829|PDB:3JBO}
RP STRUCTURE BY ELECTRON MICROSCOPY (4.70 ANGSTROMS) OF 6-161.
RX PubMed=26432834; DOI=10.1093/nar/gkv991;
RA Sun M., Li W., Blomqvist K., Das S., Hashem Y., Dvorin J.D., Frank J.;
RT "Dynamical features of the Plasmodium falciparum ribosome during
RT translation.";
RL Nucleic Acids Res. 43:10515-10524(2015).
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS17 family.
CC {ECO:0000256|ARBA:ARBA00010254, ECO:0000256|RuleBase:RU003872}.
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DR EMBL; AL844502; CAB11137.2; -; Genomic_DNA.
DR PIR; T18498; T18498.
DR RefSeq; XP_001351246.1; XM_001351210.1.
DR PDB; 3J7A; EM; 3.20 A; V=1-161.
DR PDB; 3JBN; EM; 4.70 A; V=6-161.
DR PDB; 3JBO; EM; 5.80 A; V=6-161.
DR PDB; 3JBP; EM; 6.70 A; V=6-161.
DR PDB; 6OKK; EM; 3.30 A; V=1-161.
DR PDBsum; 3J7A; -.
DR PDBsum; 3JBN; -.
DR PDBsum; 3JBO; -.
DR PDBsum; 3JBP; -.
DR PDBsum; 6OKK; -.
DR AlphaFoldDB; O77381; -.
DR SMR; O77381; -.
DR IntAct; O77381; 4.
DR STRING; 36329.O77381; -.
DR SwissPalm; O77381; -.
DR PaxDb; 5833-PFC0775w; -.
DR EnsemblProtists; CAB11137; CAB11137; PF3D7_0317600.
DR GeneID; 814490; -.
DR KEGG; pfa:PF3D7_0317600; -.
DR VEuPathDB; PlasmoDB:PF3D7_0317600; -.
DR HOGENOM; CLU_073626_0_2_1; -.
DR InParanoid; O77381; -.
DR OMA; DYEKCPF; -.
DR OrthoDB; 982046at2759; -.
DR PhylomeDB; O77381; -.
DR Reactome; R-PFA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-PFA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-PFA-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-PFA-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-PFA-72695; Formation of the ternary complex, and subsequently, the 43S complex.
DR Reactome; R-PFA-72702; Ribosomal scanning and start codon recognition.
DR Reactome; R-PFA-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-PFA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-PFA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR Proteomes; UP000001450; Chromosome 3.
DR GO; GO:0022627; C:cytosolic small ribosomal subunit; ISS:GeneDB.
DR GO; GO:0003735; F:structural constituent of ribosome; ISS:GeneDB.
DR GO; GO:0006412; P:translation; ISS:GeneDB.
DR Gene3D; 2.40.50.1000; -; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR000266; Ribosomal_uS17.
DR InterPro; IPR028333; Ribosomal_uS17_arc/euk.
DR InterPro; IPR019979; Ribosomal_uS17_CS.
DR InterPro; IPR032440; Ribosomal_uS17_N.
DR NCBIfam; TIGR03630; uS17_arch; 1.
DR PANTHER; PTHR10744:SF9; 40S RIBOSOMAL PROTEIN S11; 1.
DR PANTHER; PTHR10744; 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER; 1.
DR Pfam; PF00366; Ribosomal_S17; 1.
DR Pfam; PF16205; Ribosomal_S17_N; 1.
DR PRINTS; PR00973; RIBOSOMALS17.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00056; RIBOSOMAL_S17; 1.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:3J7A, ECO:0007829|PDB:3JBN};
KW Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW Ribonucleoprotein {ECO:0000256|RuleBase:RU003872};
KW Ribosomal protein {ECO:0000256|RuleBase:RU003872,
KW ECO:0000313|EMBL:CAB11137.2}.
FT DOMAIN 8..74
FT /note="Small ribosomal subunit protein uS17 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16205"
SQ SEQUENCE 161 AA; 18760 MW; 7119A69AA860BBFB CRC64;
MATTLDVQHE RAYQKQEGAS FFNSKKIKKG SKSYIRYWKK VGLGFATPKE AKEGVYVDKK
CPFTGNVSIR GRILKGMVIS NKMKRTIIIR RNYLHYVKKY NRFEKRHKNI PCHCSPCFDV
KEGDIVTVGQ CRPLSKTVRF NVLHVEKHQI FGSARKQFVL F
//
