ID O84272_CHLTR Unreviewed; 647 AA.
AC O84272;
DT 01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1998, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=Transglycolase/transpeptidase {ECO:0000313|EMBL:AAC67863.1};
GN Name=pbp3 {ECO:0000313|EMBL:AAC67863.1};
GN OrderedLocusNames=CT_270 {ECO:0000313|EMBL:AAC67863.1};
OS Chlamydia trachomatis (strain D/UW-3/Cx).
OC Bacteria; Chlamydiota; Chlamydiia; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=272561 {ECO:0000313|EMBL:AAC67863.1, ECO:0000313|Proteomes:UP000000431};
RN [1] {ECO:0000313|EMBL:AAC67863.1, ECO:0000313|Proteomes:UP000000431}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D/UW-3/Cx {ECO:0000313|Proteomes:UP000000431};
RX PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT trachomatis.";
RL Science 282:754-759(1998).
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DR EMBL; AE001273; AAC67863.1; -; Genomic_DNA.
DR PIR; C71534; C71534.
DR RefSeq; NP_219775.1; NC_000117.1.
DR RefSeq; WP_010725146.1; NC_000117.1.
DR AlphaFoldDB; O84272; -.
DR STRING; 272561.CT_270; -.
DR EnsemblBacteria; AAC67863; AAC67863; CT_270.
DR GeneID; 884853; -.
DR KEGG; ctr:CT_270; -.
DR PATRIC; fig|272561.5.peg.289; -.
DR HOGENOM; CLU_009289_6_4_0; -.
DR InParanoid; O84272; -.
DR OrthoDB; 9804124at2; -.
DR Proteomes; UP000000431; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IBA:GO_Central.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000431};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 267..611
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 647 AA; 73428 MW; 408D14A0CF1117C0 CRC64;
MNHRRQLTLI VVGVLSLYAL LIVRYYKIQI CDGERWAVEA ANQHEFRVKD PFQRGTFFAN
TSLRKGEKEQ FHPLAIDVTK FHLCLDAVVI PEEYRDEIAR MVVVMVGEGD YQSIRSEFDR
KSRYRKLYVS LDISIRDRIL SWWKPYAVKH KIPSNALFFI SDYQRSYPFG KLLGQVLHTL
REIKDEKSGE AFPTGGLEAY FNRLLEGENG ERKLLRSPLN RLDVDKVTKI PRDGSDIYLT
IDANVQTIAE QEIALGVLEA KARSGRAIVL NSHTGEILAL AQYPFFNPRE YREYFNCNDR
IEDTKVKAVS DVFEPGSIMK PITVAIALLA NEEMQKRAGE NLFDPYEPLD VSRRVFPGRQ
KMPLKDIVSN RYLNMYMAIQ KSSNVYMAQL ADRIVQKLGA DWYEQRLQDF GFGKRTGIEL
PAEAVGLVPS RKRFHKNGSP EWSLSTPYSL AMGYNLLATS MQMVQAYAVF GNGGFLIRPT
LVRKIVSPSG EEKILSSNPK KIRVLSEKIV ADVVRAMRFT TCLGGTGIRA ATKGYSSAGK
TGTTEKLVDG KYDKKRHIAS FIGLTPIAAL SDTAVPLVIL VSIDDPAYGV REDRTKNYMG
GRCAAPVFSR IASRVLPYLG VPLDEQLHTY REEVSQLKLL YEEWNRK
//
