ID O86693_STRCO Unreviewed; 264 AA.
AC O86693;
DT 01-NOV-1998, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1998, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Integral membrane protein {ECO:0000313|EMBL:CAA20558.1};
GN OrderedLocusNames=SCO6647 {ECO:0000313|EMBL:CAA20558.1};
GN ORFNames=SC4G2.21c {ECO:0000313|EMBL:CAA20558.1};
OS Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX NCBI_TaxID=100226 {ECO:0000313|EMBL:CAA20558.1, ECO:0000313|Proteomes:UP000001973};
RN [1] {ECO:0000313|EMBL:CAA20558.1, ECO:0000313|Proteomes:UP000001973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-471 / A3(2) / M145
RC {ECO:0000313|Proteomes:UP000001973};
RX PubMed=12000953; DOI=10.1038/417141a;
RA Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT A3(2).";
RL Nature 417:141-147(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CDP-alcohol phosphatidyltransferase class-I
CC family. {ECO:0000256|RuleBase:RU003750}.
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DR EMBL; AL939128; CAA20558.1; -; Genomic_DNA.
DR PIR; T35056; T35056.
DR RefSeq; NP_630723.1; NC_003888.3.
DR RefSeq; WP_011031073.1; NZ_VNID01000002.1.
DR AlphaFoldDB; O86693; -.
DR STRING; 100226.gene:17764305; -.
DR PaxDb; 100226-SCO6647; -.
DR PATRIC; fig|100226.15.peg.6752; -.
DR eggNOG; COG0558; Bacteria.
DR HOGENOM; CLU_076605_1_0_11; -.
DR InParanoid; O86693; -.
DR OrthoDB; 9782011at2; -.
DR Proteomes; UP000001973; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1760; -; 1.
DR InterPro; IPR000462; CDP-OH_P_trans.
DR InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR InterPro; IPR048254; CDP_ALCOHOL_P_TRANSF_CS.
DR Pfam; PF01066; CDP-OH_P_transf; 1.
DR PROSITE; PS00379; CDP_ALCOHOL_P_TRANSF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003750};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 264 AA; 27722 MW; 3E02012594FD4C6E CRC64;
MALINLNHTD DGYDAYDACP ARSVQQETAV GAGAQILLLA LLGTAIGMGT AGWLTGLAFA
FASWAVLSRA LHRSRLPSFG PANRVTLGRA TLVGGVTALV ADSFRSAPPL SLLVGLTAVA
LILDGVDGRV ARRTGTSTPL GARFDMEVDA FLILVLSVYV ALDLGPWVLL IGGMRYVFVA
AARVWPWLTA PLPPSTARKT VAALQGVLLL LAGAELLPRP GNAGVVAVAL GLLVWSFGRD
VRWLWRRSRV PAAPVTAVRE LVAQ
//
